Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis

Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis

Natural killer homeostasis is thought to be governed by gamma chain cytokines including IL-15. Here, the authors show that IL-12 can trigger the development of a distinct subset of natural killer cells with anti-tumour activity.

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Autores principales: Isabel Ohs, Maries van den Broek, Kathrin Nussbaum, Christian Münz, Sebastian J. Arnold, Sergio A. Quezada, Sonia Tugues, Burkhard Becher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/40fe5d23c28e4aabb9c6dedf9ca40c55
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