Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis
Natural killer homeostasis is thought to be governed by gamma chain cytokines including IL-15. Here, the authors show that IL-12 can trigger the development of a distinct subset of natural killer cells with anti-tumour activity.
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Auteurs principaux: | Isabel Ohs, Maries van den Broek, Kathrin Nussbaum, Christian Münz, Sebastian J. Arnold, Sergio A. Quezada, Sonia Tugues, Burkhard Becher |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
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Accès en ligne: | https://doaj.org/article/40fe5d23c28e4aabb9c6dedf9ca40c55 |
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