The Roles of Exosomes in Immunoregulation and Autoimmune Thyroid Diseases

Exosomes are extracellular microvesicles (30-150 nm) released from cells that contain proteins, lipids, RNA and DNA. They can deliver bioactive molecules and serve as carriers facilitating cell-cell communication, such as antigen presentation, inflammatory activation, autoimmune diseases (AIDs) and...

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Autores principales:	Junli Zou, Huiyong Peng, Yingzhao Liu
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	exosomes immune regulation Hashimoto’s thyroiditis Graves’ disease autoimmune thyroid diseases (AITD) Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/410862067eec4759bc13af0b9a9141ae
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spelling	oai:doaj.org-article:410862067eec4759bc13af0b9a9141ae2021-11-15T06:54:48ZThe Roles of Exosomes in Immunoregulation and Autoimmune Thyroid Diseases1664-322410.3389/fimmu.2021.757674https://doaj.org/article/410862067eec4759bc13af0b9a9141ae2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fimmu.2021.757674/fullhttps://doaj.org/toc/1664-3224Exosomes are extracellular microvesicles (30-150 nm) released from cells that contain proteins, lipids, RNA and DNA. They can deliver bioactive molecules and serve as carriers facilitating cell-cell communication, such as antigen presentation, inflammatory activation, autoimmune diseases (AIDs) and tumor metastasis. Recently, much attention has been attracted to the biology and functions of exosomes in immune regulation and AIDs, including autoimmune thyroid diseases (AITDs). Some studies have shown that exosomes are involved in the occurrence and development of AITDs, but they are still in the preliminary stage of exploration. This review mainly introduces the association of exosomes with immune regulation and emphasizes the potential role of exosomes in AITDs, aiming to provide new research strategies and directions for the pathogenesis and early diagnosis of AITDs.Junli ZouHuiyong PengHuiyong PengYingzhao LiuFrontiers Media S.A.articleexosomesimmune regulationHashimoto’s thyroiditisGraves’ diseaseautoimmune thyroid diseases (AITD)Immunologic diseases. AllergyRC581-607ENFrontiers in Immunology, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	exosomes immune regulation Hashimoto’s thyroiditis Graves’ disease autoimmune thyroid diseases (AITD) Immunologic diseases. Allergy RC581-607
spellingShingle	exosomes immune regulation Hashimoto’s thyroiditis Graves’ disease autoimmune thyroid diseases (AITD) Immunologic diseases. Allergy RC581-607 Junli Zou Huiyong Peng Huiyong Peng Yingzhao Liu The Roles of Exosomes in Immunoregulation and Autoimmune Thyroid Diseases
description	Exosomes are extracellular microvesicles (30-150 nm) released from cells that contain proteins, lipids, RNA and DNA. They can deliver bioactive molecules and serve as carriers facilitating cell-cell communication, such as antigen presentation, inflammatory activation, autoimmune diseases (AIDs) and tumor metastasis. Recently, much attention has been attracted to the biology and functions of exosomes in immune regulation and AIDs, including autoimmune thyroid diseases (AITDs). Some studies have shown that exosomes are involved in the occurrence and development of AITDs, but they are still in the preliminary stage of exploration. This review mainly introduces the association of exosomes with immune regulation and emphasizes the potential role of exosomes in AITDs, aiming to provide new research strategies and directions for the pathogenesis and early diagnosis of AITDs.
format	article
author	Junli Zou Huiyong Peng Huiyong Peng Yingzhao Liu
author_facet	Junli Zou Huiyong Peng Huiyong Peng Yingzhao Liu
author_sort	Junli Zou
title	The Roles of Exosomes in Immunoregulation and Autoimmune Thyroid Diseases
title_short	The Roles of Exosomes in Immunoregulation and Autoimmune Thyroid Diseases
title_full	The Roles of Exosomes in Immunoregulation and Autoimmune Thyroid Diseases
title_fullStr	The Roles of Exosomes in Immunoregulation and Autoimmune Thyroid Diseases
title_full_unstemmed	The Roles of Exosomes in Immunoregulation and Autoimmune Thyroid Diseases
title_sort	roles of exosomes in immunoregulation and autoimmune thyroid diseases
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/410862067eec4759bc13af0b9a9141ae
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The Roles of Exosomes in Immunoregulation and Autoimmune Thyroid Diseases

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