CLINICAL SIGNIFICANCE OF CYTOKINES SERUM LEVELS IN CHILDREN WITH CHICKEN POX

The serum levels of cytokines IL-1β, IL-8, IL-6, IFNα, IFNγ, IL-4, IL-10 were tested in ELISA in 74 children with different courses of chicken pox. Moderate severity course of chicken pox was accompanied by significant increase of IL-1β, IL-8, IFNα, IFNγ, IL-10 levels, but severe course of infection...

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Autores principales: G. F. Zheleznikova, Y. V. Lobzin, N. V. Skripchenko, G. P. Ivanova, E. Y. Skripchenko, N. E. Monakhova
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Publicado: Sankt-Peterburg : NIIÈM imeni Pastera 2015
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Acceso en línea:https://doaj.org/article/412ea11478b54616bc331a4f7e963deb
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spelling oai:doaj.org-article:412ea11478b54616bc331a4f7e963deb2021-11-22T07:09:47ZCLINICAL SIGNIFICANCE OF CYTOKINES SERUM LEVELS IN CHILDREN WITH CHICKEN POX2220-76192313-739810.15789/2220-7619-2015-1-79-84https://doaj.org/article/412ea11478b54616bc331a4f7e963deb2015-04-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/277https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398The serum levels of cytokines IL-1β, IL-8, IL-6, IFNα, IFNγ, IL-4, IL-10 were tested in ELISA in 74 children with different courses of chicken pox. Moderate severity course of chicken pox was accompanied by significant increase of IL-1β, IL-8, IFNα, IFNγ, IL-10 levels, but severe course of infection was associated with cytokine response reduction. Manifestation of varicella-zoster virus encephalitis was accompanied by the rise of IL-1β, IL-6, IFNγ and IL-10 levels during the second week of disease.G. F. ZheleznikovaY. V. LobzinN. V. SkripchenkoG. P. IvanovaE. Y. SkripchenkoN. E. MonakhovaSankt-Peterburg : NIIÈM imeni Pasteraarticlecytokineschicken poxvaricella-zoster virus encephalitischildrenInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 5, Iss 1, Pp 79-84 (2015)
institution DOAJ
collection DOAJ
language RU
topic cytokines
chicken pox
varicella-zoster virus encephalitis
children
Infectious and parasitic diseases
RC109-216
spellingShingle cytokines
chicken pox
varicella-zoster virus encephalitis
children
Infectious and parasitic diseases
RC109-216
G. F. Zheleznikova
Y. V. Lobzin
N. V. Skripchenko
G. P. Ivanova
E. Y. Skripchenko
N. E. Monakhova
CLINICAL SIGNIFICANCE OF CYTOKINES SERUM LEVELS IN CHILDREN WITH CHICKEN POX
description The serum levels of cytokines IL-1β, IL-8, IL-6, IFNα, IFNγ, IL-4, IL-10 were tested in ELISA in 74 children with different courses of chicken pox. Moderate severity course of chicken pox was accompanied by significant increase of IL-1β, IL-8, IFNα, IFNγ, IL-10 levels, but severe course of infection was associated with cytokine response reduction. Manifestation of varicella-zoster virus encephalitis was accompanied by the rise of IL-1β, IL-6, IFNγ and IL-10 levels during the second week of disease.
format article
author G. F. Zheleznikova
Y. V. Lobzin
N. V. Skripchenko
G. P. Ivanova
E. Y. Skripchenko
N. E. Monakhova
author_facet G. F. Zheleznikova
Y. V. Lobzin
N. V. Skripchenko
G. P. Ivanova
E. Y. Skripchenko
N. E. Monakhova
author_sort G. F. Zheleznikova
title CLINICAL SIGNIFICANCE OF CYTOKINES SERUM LEVELS IN CHILDREN WITH CHICKEN POX
title_short CLINICAL SIGNIFICANCE OF CYTOKINES SERUM LEVELS IN CHILDREN WITH CHICKEN POX
title_full CLINICAL SIGNIFICANCE OF CYTOKINES SERUM LEVELS IN CHILDREN WITH CHICKEN POX
title_fullStr CLINICAL SIGNIFICANCE OF CYTOKINES SERUM LEVELS IN CHILDREN WITH CHICKEN POX
title_full_unstemmed CLINICAL SIGNIFICANCE OF CYTOKINES SERUM LEVELS IN CHILDREN WITH CHICKEN POX
title_sort clinical significance of cytokines serum levels in children with chicken pox
publisher Sankt-Peterburg : NIIÈM imeni Pastera
publishDate 2015
url https://doaj.org/article/412ea11478b54616bc331a4f7e963deb
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