Comparison Level of Interferon γ in Tuberculosis and Non Tuberculosis Pleural Effusion

BACKGROUND AND OBJECTIVE: In our country the most common cause of exudative pleural effusion is tuberculosis pleural effusion. Diagnosis of tuberculosis pleurisy is difficult because of its nonspecific clinical presentation and insufficient efficiency of traditional diagnostic methods. The aim of th...

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Autores principales:	M Shahriar, B Narouie, AA Niazi, AS Sheikhzadeh, M Ghasemi Rad
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2009
Materias:	tuberculosis pleurisy pleural effusion gamma interferon Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/4131029f4ca04810a709186c8ff29c98
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spelling	oai:doaj.org-article:4131029f4ca04810a709186c8ff29c982021-11-10T09:02:52ZComparison Level of Interferon γ in Tuberculosis and Non Tuberculosis Pleural Effusion1561-41072251-7170https://doaj.org/article/4131029f4ca04810a709186c8ff29c982009-08-01T00:00:00Zhttp://jbums.org/article-1-3224-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: In our country the most common cause of exudative pleural effusion is tuberculosis pleural effusion. Diagnosis of tuberculosis pleurisy is difficult because of its nonspecific clinical presentation and insufficient efficiency of traditional diagnostic methods. The aim of this study was to investigate the level of interferon γ (INFγ) in tuberculosis and non tuberculosis pleural effusion.METHODS: The subjects of this case-control study were consisted of 20 patients with TB pleural effusion and 32 non-TB pleural effusion the diagnosis of tuberculosis pleurisy can be established by culture of the pleural fluid, needle biopsy of the pleura or thoracoscopy. Demographic characteristics and pleural fluid chemistry and the level of interferon γ were compared in two groups. FINDINGS: Demographic characteristics, including age, sex, job and nationality were almost the same in both groups. Dyspnea was the most common symptom in both groups. Most of our patients were non smoker and PPD negative. Pleural effusion was yellow in both groups and cholesterol and triglyceride level were not significantly different, low glucose and high protein levels were found in tuberculosis plural fluid. There wasn’t any significant difference in lymphocyte and neutrophil count between two groups. INFγ was 99±94.7 mg in TB pleural effusion and 8.4±2.3 mg in non– TB pleural effusion that was significantly higher in TB pleural effusion (p=0.001)CONCLUSION: The results showed that INF γ level in TB pleural effusion is more than non TB. But now it is not cost- effective so we can’t suggest it as a routine diagnostic method in pleural effusion assessment but will be useful only in doubtful cases.M Shahriar,B Narouie,AA NiaziAS SheikhzadehM Ghasemi RadBabol University of Medical Sciencesarticletuberculosis pleurisypleural effusiongamma interferonMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 11, Iss 3, Pp 48-53 (2009)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	tuberculosis pleurisy pleural effusion gamma interferon Medicine R Medicine (General) R5-920
spellingShingle	tuberculosis pleurisy pleural effusion gamma interferon Medicine R Medicine (General) R5-920 M Shahriar, B Narouie, AA Niazi AS Sheikhzadeh M Ghasemi Rad Comparison Level of Interferon γ in Tuberculosis and Non Tuberculosis Pleural Effusion
description	BACKGROUND AND OBJECTIVE: In our country the most common cause of exudative pleural effusion is tuberculosis pleural effusion. Diagnosis of tuberculosis pleurisy is difficult because of its nonspecific clinical presentation and insufficient efficiency of traditional diagnostic methods. The aim of this study was to investigate the level of interferon γ (INFγ) in tuberculosis and non tuberculosis pleural effusion.METHODS: The subjects of this case-control study were consisted of 20 patients with TB pleural effusion and 32 non-TB pleural effusion the diagnosis of tuberculosis pleurisy can be established by culture of the pleural fluid, needle biopsy of the pleura or thoracoscopy. Demographic characteristics and pleural fluid chemistry and the level of interferon γ were compared in two groups. FINDINGS: Demographic characteristics, including age, sex, job and nationality were almost the same in both groups. Dyspnea was the most common symptom in both groups. Most of our patients were non smoker and PPD negative. Pleural effusion was yellow in both groups and cholesterol and triglyceride level were not significantly different, low glucose and high protein levels were found in tuberculosis plural fluid. There wasn’t any significant difference in lymphocyte and neutrophil count between two groups. INFγ was 99±94.7 mg in TB pleural effusion and 8.4±2.3 mg in non– TB pleural effusion that was significantly higher in TB pleural effusion (p=0.001)CONCLUSION: The results showed that INF γ level in TB pleural effusion is more than non TB. But now it is not cost- effective so we can’t suggest it as a routine diagnostic method in pleural effusion assessment but will be useful only in doubtful cases.
format	article
author	M Shahriar, B Narouie, AA Niazi AS Sheikhzadeh M Ghasemi Rad
author_facet	M Shahriar, B Narouie, AA Niazi AS Sheikhzadeh M Ghasemi Rad
author_sort	M Shahriar,
title	Comparison Level of Interferon γ in Tuberculosis and Non Tuberculosis Pleural Effusion
title_short	Comparison Level of Interferon γ in Tuberculosis and Non Tuberculosis Pleural Effusion
title_full	Comparison Level of Interferon γ in Tuberculosis and Non Tuberculosis Pleural Effusion
title_fullStr	Comparison Level of Interferon γ in Tuberculosis and Non Tuberculosis Pleural Effusion
title_full_unstemmed	Comparison Level of Interferon γ in Tuberculosis and Non Tuberculosis Pleural Effusion
title_sort	comparison level of interferon γ in tuberculosis and non tuberculosis pleural effusion
publisher	Babol University of Medical Sciences
publishDate	2009
url	https://doaj.org/article/4131029f4ca04810a709186c8ff29c98
work_keys_str_mv	AT mshahriar comparisonlevelofinterferongintuberculosisandnontuberculosispleuraleffusion AT bnarouie comparisonlevelofinterferongintuberculosisandnontuberculosispleuraleffusion AT aaniazi comparisonlevelofinterferongintuberculosisandnontuberculosispleuraleffusion AT assheikhzadeh comparisonlevelofinterferongintuberculosisandnontuberculosispleuraleffusion AT mghasemirad comparisonlevelofinterferongintuberculosisandnontuberculosispleuraleffusion
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Comparison Level of Interferon γ in Tuberculosis and Non Tuberculosis Pleural Effusion

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