LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain

Epigenetic regulation plays a key role in cortical development. Here the authors show that Rcor2, a co-repressor of the histone demethylase LSD1/KDM1A complex, regulates neural progenitor cell proliferation and cortical neurogenesis by repressing sonic hedgehog signaling.

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Autores principales:	Yixuan Wang, Qian Wu, Peng Yang, Chenfei Wang, Jing Liu, Wenyu Ding, Wensu Liu, Ye Bai, Yuanyuan Yang, Hong Wang, Shaorong Gao, Xiaoqun Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/41341f2f73fe4c43bb849a0a45be92ff
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spelling	oai:doaj.org-article:41341f2f73fe4c43bb849a0a45be92ff2021-12-02T15:35:46ZLSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain10.1038/ncomms104812041-1723https://doaj.org/article/41341f2f73fe4c43bb849a0a45be92ff2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10481https://doaj.org/toc/2041-1723Epigenetic regulation plays a key role in cortical development. Here the authors show that Rcor2, a co-repressor of the histone demethylase LSD1/KDM1A complex, regulates neural progenitor cell proliferation and cortical neurogenesis by repressing sonic hedgehog signaling.Yixuan WangQian WuPeng YangChenfei WangJing LiuWenyu DingWensu LiuYe BaiYuanyuan YangHong WangShaorong GaoXiaoqun WangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yixuan Wang Qian Wu Peng Yang Chenfei Wang Jing Liu Wenyu Ding Wensu Liu Ye Bai Yuanyuan Yang Hong Wang Shaorong Gao Xiaoqun Wang LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain
description	Epigenetic regulation plays a key role in cortical development. Here the authors show that Rcor2, a co-repressor of the histone demethylase LSD1/KDM1A complex, regulates neural progenitor cell proliferation and cortical neurogenesis by repressing sonic hedgehog signaling.
format	article
author	Yixuan Wang Qian Wu Peng Yang Chenfei Wang Jing Liu Wenyu Ding Wensu Liu Ye Bai Yuanyuan Yang Hong Wang Shaorong Gao Xiaoqun Wang
author_facet	Yixuan Wang Qian Wu Peng Yang Chenfei Wang Jing Liu Wenyu Ding Wensu Liu Ye Bai Yuanyuan Yang Hong Wang Shaorong Gao Xiaoqun Wang
author_sort	Yixuan Wang
title	LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain
title_short	LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain
title_full	LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain
title_fullStr	LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain
title_full_unstemmed	LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain
title_sort	lsd1 co-repressor rcor2 orchestrates neurogenesis in the developing mouse brain
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/41341f2f73fe4c43bb849a0a45be92ff
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LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain

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