LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain

LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain

Epigenetic regulation plays a key role in cortical development. Here the authors show that Rcor2, a co-repressor of the histone demethylase LSD1/KDM1A complex, regulates neural progenitor cell proliferation and cortical neurogenesis by repressing sonic hedgehog signaling.

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Detalles Bibliográficos
Autores principales: Yixuan Wang, Qian Wu, Peng Yang, Chenfei Wang, Jing Liu, Wenyu Ding, Wensu Liu, Ye Bai, Yuanyuan Yang, Hong Wang, Shaorong Gao, Xiaoqun Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
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Acceso en línea:https://doaj.org/article/41341f2f73fe4c43bb849a0a45be92ff
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