Comparative Study between Sertraline and Omega-3 Supplementation in The Treatment of Uremic Pruritus in Hemodialysis Patient

Background: Pruritus in uremic patients decreases the quality of life because of sleep disturbances, depression and anxiety, thus, pruritus remains an important health issue in ESRD patients. Aim of the work:To evaluate the efficacy and safety of sertraline versus omega 3 supplementation in the tr...

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Autores principales:	Mohamed Elghareib, Ibrahim Fouda, Hassan Khodair, Ahmed Al-Adl
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2020
Materias:	omega-3 sertraline pruritus end-stage renal disease uremic renal Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/413458e42eae4cb1b2230779877ac19d
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spelling	oai:doaj.org-article:413458e42eae4cb1b2230779877ac19d2021-12-02T10:38:27ZComparative Study between Sertraline and Omega-3 Supplementation in The Treatment of Uremic Pruritus in Hemodialysis Patient2636-41742682-378010.21608/ijma.2020.31065.1127https://doaj.org/article/413458e42eae4cb1b2230779877ac19d2020-07-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_95625_aa242e2125c6a95e5a740ceee9c90304.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Pruritus in uremic patients decreases the quality of life because of sleep disturbances, depression and anxiety, thus, pruritus remains an important health issue in ESRD patients. Aim of the work:To evaluate the efficacy and safety of sertraline versus omega 3 supplementation in the treatment of uremic pruritus. Patients and Methods:This randomized case control study was conducted on patients with ESRD patients .All studied subjects had been collected from the Al-Azhar hospital [Damietta] Dialysis Center. This study had been carried out on 50 patients divided into: Group [A] : consists of 25patients had been received 50 mg sertraline twice a day for 8 weeks. Group [B]: consists of 25 patients and had been receive 3 gm omega-3 daily. Results: Although pruritus severity decrease signiﬁcantly in both groups and both scoring systems [P<0.001], the reduction was signiﬁcantly more in sertraline group [p Conclusion: Omega-3 fatty acids found to be effective in decreasing of uremic pruritus. So, it seems that Omega-3 fatty acids could be used as an efficient drug for treatment of pruritus in uremic patients. The present study showed that low-dose sertraline was effective for antihistamine-refractory uremic pruritus than omeg3 in renal palliative care patients.Mohamed ElghareibIbrahim FoudaHassan KhodairAhmed Al-AdlAl-Azhar University, Faculty of Medicine (Damietta)articleomega-3sertralinepruritusend-stage renal diseaseuremicrenalMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 3, Pp 655-660 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	omega-3 sertraline pruritus end-stage renal disease uremic renal Medicine (General) R5-920
spellingShingle	omega-3 sertraline pruritus end-stage renal disease uremic renal Medicine (General) R5-920 Mohamed Elghareib Ibrahim Fouda Hassan Khodair Ahmed Al-Adl Comparative Study between Sertraline and Omega-3 Supplementation in The Treatment of Uremic Pruritus in Hemodialysis Patient
description	Background: Pruritus in uremic patients decreases the quality of life because of sleep disturbances, depression and anxiety, thus, pruritus remains an important health issue in ESRD patients. Aim of the work:To evaluate the efficacy and safety of sertraline versus omega 3 supplementation in the treatment of uremic pruritus. Patients and Methods:This randomized case control study was conducted on patients with ESRD patients .All studied subjects had been collected from the Al-Azhar hospital [Damietta] Dialysis Center. This study had been carried out on 50 patients divided into: Group [A] : consists of 25patients had been received 50 mg sertraline twice a day for 8 weeks. Group [B]: consists of 25 patients and had been receive 3 gm omega-3 daily. Results: Although pruritus severity decrease signiﬁcantly in both groups and both scoring systems [P<0.001], the reduction was signiﬁcantly more in sertraline group [p Conclusion: Omega-3 fatty acids found to be effective in decreasing of uremic pruritus. So, it seems that Omega-3 fatty acids could be used as an efficient drug for treatment of pruritus in uremic patients. The present study showed that low-dose sertraline was effective for antihistamine-refractory uremic pruritus than omeg3 in renal palliative care patients.
format	article
author	Mohamed Elghareib Ibrahim Fouda Hassan Khodair Ahmed Al-Adl
author_facet	Mohamed Elghareib Ibrahim Fouda Hassan Khodair Ahmed Al-Adl
author_sort	Mohamed Elghareib
title	Comparative Study between Sertraline and Omega-3 Supplementation in The Treatment of Uremic Pruritus in Hemodialysis Patient
title_short	Comparative Study between Sertraline and Omega-3 Supplementation in The Treatment of Uremic Pruritus in Hemodialysis Patient
title_full	Comparative Study between Sertraline and Omega-3 Supplementation in The Treatment of Uremic Pruritus in Hemodialysis Patient
title_fullStr	Comparative Study between Sertraline and Omega-3 Supplementation in The Treatment of Uremic Pruritus in Hemodialysis Patient
title_full_unstemmed	Comparative Study between Sertraline and Omega-3 Supplementation in The Treatment of Uremic Pruritus in Hemodialysis Patient
title_sort	comparative study between sertraline and omega-3 supplementation in the treatment of uremic pruritus in hemodialysis patient
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2020
url	https://doaj.org/article/413458e42eae4cb1b2230779877ac19d
work_keys_str_mv	AT mohamedelghareib comparativestudybetweensertralineandomega3supplementationinthetreatmentofuremicpruritusinhemodialysispatient AT ibrahimfouda comparativestudybetweensertralineandomega3supplementationinthetreatmentofuremicpruritusinhemodialysispatient AT hassankhodair comparativestudybetweensertralineandomega3supplementationinthetreatmentofuremicpruritusinhemodialysispatient AT ahmedaladl comparativestudybetweensertralineandomega3supplementationinthetreatmentofuremicpruritusinhemodialysispatient
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Comparative Study between Sertraline and Omega-3 Supplementation in The Treatment of Uremic Pruritus in Hemodialysis Patient

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