Inhibitory gain modulation of defense behaviors by zona incerta

Zona incerta (ZI) is an inhibitory subthalamic nucleus with diverse connectivity yet its functional importance has not been extensively studied. Here the authors report that ZI receives mPFC input and can modulate both innate and learned defensive behaviors via its inhibitory projection to the PAG.

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Autores principales: Xiao-lin Chou, Xiyue Wang, Zheng-gang Zhang, Li Shen, Brian Zingg, Junxiang Huang, Wen Zhong, Lukas Mesik, Li I. Zhang, Huizhong Whit Tao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/414397bc71694fb6a0f6185a6a723df3
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spelling oai:doaj.org-article:414397bc71694fb6a0f6185a6a723df32021-12-02T17:31:46ZInhibitory gain modulation of defense behaviors by zona incerta10.1038/s41467-018-03581-62041-1723https://doaj.org/article/414397bc71694fb6a0f6185a6a723df32018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03581-6https://doaj.org/toc/2041-1723Zona incerta (ZI) is an inhibitory subthalamic nucleus with diverse connectivity yet its functional importance has not been extensively studied. Here the authors report that ZI receives mPFC input and can modulate both innate and learned defensive behaviors via its inhibitory projection to the PAG.Xiao-lin ChouXiyue WangZheng-gang ZhangLi ShenBrian ZinggJunxiang HuangWen ZhongLukas MesikLi I. ZhangHuizhong Whit TaoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiao-lin Chou
Xiyue Wang
Zheng-gang Zhang
Li Shen
Brian Zingg
Junxiang Huang
Wen Zhong
Lukas Mesik
Li I. Zhang
Huizhong Whit Tao
Inhibitory gain modulation of defense behaviors by zona incerta
description Zona incerta (ZI) is an inhibitory subthalamic nucleus with diverse connectivity yet its functional importance has not been extensively studied. Here the authors report that ZI receives mPFC input and can modulate both innate and learned defensive behaviors via its inhibitory projection to the PAG.
format article
author Xiao-lin Chou
Xiyue Wang
Zheng-gang Zhang
Li Shen
Brian Zingg
Junxiang Huang
Wen Zhong
Lukas Mesik
Li I. Zhang
Huizhong Whit Tao
author_facet Xiao-lin Chou
Xiyue Wang
Zheng-gang Zhang
Li Shen
Brian Zingg
Junxiang Huang
Wen Zhong
Lukas Mesik
Li I. Zhang
Huizhong Whit Tao
author_sort Xiao-lin Chou
title Inhibitory gain modulation of defense behaviors by zona incerta
title_short Inhibitory gain modulation of defense behaviors by zona incerta
title_full Inhibitory gain modulation of defense behaviors by zona incerta
title_fullStr Inhibitory gain modulation of defense behaviors by zona incerta
title_full_unstemmed Inhibitory gain modulation of defense behaviors by zona incerta
title_sort inhibitory gain modulation of defense behaviors by zona incerta
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/414397bc71694fb6a0f6185a6a723df3
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