Inhibitory gain modulation of defense behaviors by zona incerta
Zona incerta (ZI) is an inhibitory subthalamic nucleus with diverse connectivity yet its functional importance has not been extensively studied. Here the authors report that ZI receives mPFC input and can modulate both innate and learned defensive behaviors via its inhibitory projection to the PAG.
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Nature Portfolio
2018
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oai:doaj.org-article:414397bc71694fb6a0f6185a6a723df32021-12-02T17:31:46ZInhibitory gain modulation of defense behaviors by zona incerta10.1038/s41467-018-03581-62041-1723https://doaj.org/article/414397bc71694fb6a0f6185a6a723df32018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03581-6https://doaj.org/toc/2041-1723Zona incerta (ZI) is an inhibitory subthalamic nucleus with diverse connectivity yet its functional importance has not been extensively studied. Here the authors report that ZI receives mPFC input and can modulate both innate and learned defensive behaviors via its inhibitory projection to the PAG.Xiao-lin ChouXiyue WangZheng-gang ZhangLi ShenBrian ZinggJunxiang HuangWen ZhongLukas MesikLi I. ZhangHuizhong Whit TaoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Xiao-lin Chou Xiyue Wang Zheng-gang Zhang Li Shen Brian Zingg Junxiang Huang Wen Zhong Lukas Mesik Li I. Zhang Huizhong Whit Tao Inhibitory gain modulation of defense behaviors by zona incerta |
description |
Zona incerta (ZI) is an inhibitory subthalamic nucleus with diverse connectivity yet its functional importance has not been extensively studied. Here the authors report that ZI receives mPFC input and can modulate both innate and learned defensive behaviors via its inhibitory projection to the PAG. |
format |
article |
author |
Xiao-lin Chou Xiyue Wang Zheng-gang Zhang Li Shen Brian Zingg Junxiang Huang Wen Zhong Lukas Mesik Li I. Zhang Huizhong Whit Tao |
author_facet |
Xiao-lin Chou Xiyue Wang Zheng-gang Zhang Li Shen Brian Zingg Junxiang Huang Wen Zhong Lukas Mesik Li I. Zhang Huizhong Whit Tao |
author_sort |
Xiao-lin Chou |
title |
Inhibitory gain modulation of defense behaviors by zona incerta |
title_short |
Inhibitory gain modulation of defense behaviors by zona incerta |
title_full |
Inhibitory gain modulation of defense behaviors by zona incerta |
title_fullStr |
Inhibitory gain modulation of defense behaviors by zona incerta |
title_full_unstemmed |
Inhibitory gain modulation of defense behaviors by zona incerta |
title_sort |
inhibitory gain modulation of defense behaviors by zona incerta |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/414397bc71694fb6a0f6185a6a723df3 |
work_keys_str_mv |
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1718380485397184512 |