SSTP1, a Host Defense Peptide, Exploits the Immunomodulatory IL6 Pathway to Induce Apoptosis in Cancer Cells

While the immunomodulatory pathways initiated in immune cells contribute to therapeutic response, their activation in cancer cells play a role in cancer progression. Also, many of the aberrantly expressed immunomodulators on cancer cells are considered as therapeutic targets. Here, we introduce host...

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Auteurs principaux:	Shyla Gopalakrishnan, Soumya Krishnan Uma, Gayathri Mohan, Amrutha Mohan, Geetha Shanmugam, Vineeth T. V. Kumar, Sreekumar J, Sivakumar K. Chandrika, Dileep Vasudevan, Sai Ravi Chandra Nori, Shijulal Nelson Sathi, Sanil George, Tessy Thomas Maliekal
Format:	article
Langue:	EN
Publié:	Frontiers Media S.A. 2021
Sujets:	host defense peptides temporins immunoregulation JNK/AP1 pathway cancer apoptosis Immunologic diseases. Allergy RC581-607
Accès en ligne:	https://doaj.org/article/41457526d2a84c1d81a6c729af043fa3
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SSTP1, a Host Defense Peptide, Exploits the Immunomodulatory IL6 Pathway to Induce Apoptosis in Cancer Cells

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