Radiotherapy suppresses angiogenesis in mice through TGF-betaRI/ALK5-dependent inhibition of endothelial cell sprouting.
<h4>Background</h4>Radiotherapy is widely used to treat cancer. While rapidly dividing cancer cells are naturally considered the main target of radiotherapy, emerging evidence indicates that radiotherapy also affects endothelial cell functions, and possibly also their angiogenic capacity...
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Autores principales: | Natsuko Imaizumi, Yan Monnier, Monika Hegi, René-Olivier Mirimanoff, Curzio Rüegg |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/414946e725da4a358df079dd9a4e594f |
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