Radiotherapy suppresses angiogenesis in mice through TGF-betaRI/ALK5-dependent inhibition of endothelial cell sprouting.

<h4>Background</h4>Radiotherapy is widely used to treat cancer. While rapidly dividing cancer cells are naturally considered the main target of radiotherapy, emerging evidence indicates that radiotherapy also affects endothelial cell functions, and possibly also their angiogenic capacity...

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Bibliographic Details
Main Authors: Natsuko Imaizumi, Yan Monnier, Monika Hegi, René-Olivier Mirimanoff, Curzio Rüegg
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
Subjects:
R
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Online Access:https://doaj.org/article/414946e725da4a358df079dd9a4e594f
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