4D Visualization of replication foci in mammalian cells corresponding to individual replicons

Whether replication happens at individual replicons or in replication factories is a controversial debate. Here the authors use super-resolution microscopy and analysis of replication fork speed to present evidence in favour of replicons.

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Detalles Bibliográficos
Autores principales: V. O. Chagin, C. S. Casas-Delucchi, M. Reinhart, L. Schermelleh, Y. Markaki, A. Maiser, J. J. Bolius, A. Bensimon, M. Fillies, P. Domaing, Y. M. Rozanov, H. Leonhardt, M. C. Cardoso
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/4153e26953cb4527b65282d65123c565
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Sumario:Whether replication happens at individual replicons or in replication factories is a controversial debate. Here the authors use super-resolution microscopy and analysis of replication fork speed to present evidence in favour of replicons.