Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death
Apoptosis is a cellular process that eliminates damaged or superfluous cells. Here the authors show that cells undergoing apoptotic stresss secrete the growth factor FGF2, which upregulates pro-survival BCL-2 proteins in neighbouring cells, thereby promoting their survival.
Guardado en:
Autores principales: | Florian J. Bock, Egor Sedov, Elle Koren, Anna L. Koessinger, Catherine Cloix, Désirée Zerbst, Dimitris Athineos, Jayanthi Anand, Kirsteen J. Campbell, Karen Blyth, Yaron Fuchs, Stephen W. G. Tait |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/415af44f66154f70b3f34ec84435ad64 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
por: Alona Feldman, et al.
Publicado: (2019) -
ARTS mediates apoptosis and regeneration of the intestinal stem cell niche
por: Elle Koren, et al.
Publicado: (2018) -
Non-cell-autonomous activation of IL-6/STAT3 signaling mediates FGF19-driven hepatocarcinogenesis
por: Mei Zhou, et al.
Publicado: (2017) -
Fgf21 regulates T-cell development in the neonatal and juvenile thymus
por: Yoshiaki Nakayama, et al.
Publicado: (2017) -
Specific inhibition of FGF5-induced cell proliferation by RNA aptamers
por: Ryo Amano, et al.
Publicado: (2021)