Biophysical characterization and membrane interaction of the two fusion loops of glycoprotein B from herpes simplex type I virus.

Biophysical characterization and membrane interaction of the two fusion loops of glycoprotein B from herpes simplex type I virus.

The molecular mechanism of entry of herpesviruses requires a multicomponent fusion system. Cell invasion by Herpes simplex virus (HSV) requires four virally encoded glycoproteins: namely gD, gB and gH/gL. The role of gB has remained elusive until recently when the crystal structure of HSV-1 gB becam...

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Autores principales: Annarita Falanga, Rossella Tarallo, Giuseppe Vitiello, Mariateresa Vitiello, Emiliana Perillo, Marco Cantisani, Gerardino D'Errico, Massimiliano Galdiero, Stefania Galdiero
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/415c9aee102c4bedb37923a9df19e764
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