Durable protection against repeated penile exposures to simian-human immunodeficiency virus by broadly neutralizing antibodies

Durable protection against repeated penile exposures to simian-human immunodeficiency virus by broadly neutralizing antibodies

Here, using a repeat-exposure penile SHIV infection model in macaques, the authors show that a single subcutaneous administration of a broadly neutralizing antibody (bNAb) exerts long-acting protection against both penile and vaginal virus exposure, which highlights bNAbs as a potential therapeutic...

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Autores principales: David A. Garber, Debra R. Adams, Patricia Guenthner, James Mitchell, Kristen Kelley, Till Schoofs, Anna Gazumyan, Martha Nason, Michael S. Seaman, Janet McNicholl, Michel C. Nussenzweig, Walid Heneine
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/415ea2495b55415ba7d408c549af42a5
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