Association of PM2.5 exposure with hospitalization for cardiovascular disease in elderly individuals in Japan

Abstract Although exposure to particulate matter with aerodynamic diameters ≤ 2.5 µm (PM2.5) influences cardiovascular disease (CVD), its association with CVD-related hospitalizations of super-aged patients in Japan remains uncertain. We investigated the relationship between short-term PM2.5 exposur...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Toshiki Kaihara, Kihei Yoneyama, Michikazu Nakai, Takumi Higuma, Yoko Sumita, Yoshihiro Miyamoto, Mika Watanabe, Masaki Izumo, Yuki Ishibashi, Yasuhiro Tanabe, Tomoo Harada, Satoshi Yasuda, Hisao Ogawa, Yoshihiro J. Akashi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/41630a36a8f0430ea5f7dac428810b52
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:41630a36a8f0430ea5f7dac428810b52
record_format	dspace
spelling	oai:doaj.org-article:41630a36a8f0430ea5f7dac428810b522021-12-02T17:02:13ZAssociation of PM2.5 exposure with hospitalization for cardiovascular disease in elderly individuals in Japan10.1038/s41598-021-89290-52045-2322https://doaj.org/article/41630a36a8f0430ea5f7dac428810b522021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-89290-5https://doaj.org/toc/2045-2322Abstract Although exposure to particulate matter with aerodynamic diameters ≤ 2.5 µm (PM2.5) influences cardiovascular disease (CVD), its association with CVD-related hospitalizations of super-aged patients in Japan remains uncertain. We investigated the relationship between short-term PM2.5 exposure and CVD-related hospitalizations, lengths of hospital stays, and medical expenses. We analyzed the Japanese national database of patients with CVD (835,405) admitted to acute-care hospitals between 2012 and 2014. Patients with planned hospitalizations and those with missing PM2.5 exposure data were excluded. We classified the included patients into five quintiles based on their PM2.5 exposure: PM-5, -4, -3, -2, and -1 groups, in descending order of concentration. Compared with the PM-1 group, the other groups had higher hospitalization rates. The PM-3, -4, and -5 groups exhibited increased hospitalization durations and medical expenses, compared with the PM-1 group. Interestingly, the hospitalization period was longer for the ≥ 90-year-old group than for the ≤ 64-year-old group, yet the medical expenses were lower for the former group. Short-term PM2.5 exposure is associated with increased CVD-related hospitalizations, hospitalization durations, and medical expenses. The effects of incident CVDs were more marked in elderly than in younger patients. National PM2.5 concentrations should be reduced and the public should be aware of the risks.Toshiki KaiharaKihei YoneyamaMichikazu NakaiTakumi HigumaYoko SumitaYoshihiro MiyamotoMika WatanabeMasaki IzumoYuki IshibashiYasuhiro TanabeTomoo HaradaSatoshi YasudaHisao OgawaYoshihiro J. AkashiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Toshiki Kaihara Kihei Yoneyama Michikazu Nakai Takumi Higuma Yoko Sumita Yoshihiro Miyamoto Mika Watanabe Masaki Izumo Yuki Ishibashi Yasuhiro Tanabe Tomoo Harada Satoshi Yasuda Hisao Ogawa Yoshihiro J. Akashi Association of PM2.5 exposure with hospitalization for cardiovascular disease in elderly individuals in Japan
description	Abstract Although exposure to particulate matter with aerodynamic diameters ≤ 2.5 µm (PM2.5) influences cardiovascular disease (CVD), its association with CVD-related hospitalizations of super-aged patients in Japan remains uncertain. We investigated the relationship between short-term PM2.5 exposure and CVD-related hospitalizations, lengths of hospital stays, and medical expenses. We analyzed the Japanese national database of patients with CVD (835,405) admitted to acute-care hospitals between 2012 and 2014. Patients with planned hospitalizations and those with missing PM2.5 exposure data were excluded. We classified the included patients into five quintiles based on their PM2.5 exposure: PM-5, -4, -3, -2, and -1 groups, in descending order of concentration. Compared with the PM-1 group, the other groups had higher hospitalization rates. The PM-3, -4, and -5 groups exhibited increased hospitalization durations and medical expenses, compared with the PM-1 group. Interestingly, the hospitalization period was longer for the ≥ 90-year-old group than for the ≤ 64-year-old group, yet the medical expenses were lower for the former group. Short-term PM2.5 exposure is associated with increased CVD-related hospitalizations, hospitalization durations, and medical expenses. The effects of incident CVDs were more marked in elderly than in younger patients. National PM2.5 concentrations should be reduced and the public should be aware of the risks.
format	article
author	Toshiki Kaihara Kihei Yoneyama Michikazu Nakai Takumi Higuma Yoko Sumita Yoshihiro Miyamoto Mika Watanabe Masaki Izumo Yuki Ishibashi Yasuhiro Tanabe Tomoo Harada Satoshi Yasuda Hisao Ogawa Yoshihiro J. Akashi
author_facet	Toshiki Kaihara Kihei Yoneyama Michikazu Nakai Takumi Higuma Yoko Sumita Yoshihiro Miyamoto Mika Watanabe Masaki Izumo Yuki Ishibashi Yasuhiro Tanabe Tomoo Harada Satoshi Yasuda Hisao Ogawa Yoshihiro J. Akashi
author_sort	Toshiki Kaihara
title	Association of PM2.5 exposure with hospitalization for cardiovascular disease in elderly individuals in Japan
title_short	Association of PM2.5 exposure with hospitalization for cardiovascular disease in elderly individuals in Japan
title_full	Association of PM2.5 exposure with hospitalization for cardiovascular disease in elderly individuals in Japan
title_fullStr	Association of PM2.5 exposure with hospitalization for cardiovascular disease in elderly individuals in Japan
title_full_unstemmed	Association of PM2.5 exposure with hospitalization for cardiovascular disease in elderly individuals in Japan
title_sort	association of pm2.5 exposure with hospitalization for cardiovascular disease in elderly individuals in japan
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/41630a36a8f0430ea5f7dac428810b52
work_keys_str_mv	AT toshikikaihara associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT kiheiyoneyama associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT michikazunakai associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT takumihiguma associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT yokosumita associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT yoshihiromiyamoto associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT mikawatanabe associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT masakiizumo associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT yukiishibashi associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT yasuhirotanabe associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT tomooharada associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT satoshiyasuda associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT hisaoogawa associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan AT yoshihirojakashi associationofpm25exposurewithhospitalizationforcardiovasculardiseaseinelderlyindividualsinjapan
_version_	1718381902557085696

Association of PM2.5 exposure with hospitalization for cardiovascular disease in elderly individuals in Japan

Ejemplares similares