Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine

Using a Streptococcus pneumoniae human challenge model, the authors here show that baseline nasal microbiota profiles are associated with pneumococcal acquisition and density, independent of live-attenuated influenza vaccine (LAIV) administration, and with mucosal cytokine responses to LAIV.

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Autores principales: Wouter A. A. de Steenhuijsen Piters, Simon P. Jochems, Elena Mitsi, Jamie Rylance, Sherin Pojar, Elissavet Nikolaou, Esther L. German, Mark Holloway, Beatriz F. Carniel, Mei Ling J. N. Chu, Kayleigh Arp, Elisabeth A. M. Sanders, Daniela M. Ferreira, Debby Bogaert
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/41664ac4244044f8a670c8b1459330bb
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spelling oai:doaj.org-article:41664ac4244044f8a670c8b1459330bb2021-12-02T14:39:03ZInteraction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine10.1038/s41467-019-10814-92041-1723https://doaj.org/article/41664ac4244044f8a670c8b1459330bb2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10814-9https://doaj.org/toc/2041-1723Using a Streptococcus pneumoniae human challenge model, the authors here show that baseline nasal microbiota profiles are associated with pneumococcal acquisition and density, independent of live-attenuated influenza vaccine (LAIV) administration, and with mucosal cytokine responses to LAIV.Wouter A. A. de Steenhuijsen PitersSimon P. JochemsElena MitsiJamie RylanceSherin PojarElissavet NikolaouEsther L. GermanMark HollowayBeatriz F. CarnielMei Ling J. N. ChuKayleigh ArpElisabeth A. M. SandersDaniela M. FerreiraDebby BogaertNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wouter A. A. de Steenhuijsen Piters
Simon P. Jochems
Elena Mitsi
Jamie Rylance
Sherin Pojar
Elissavet Nikolaou
Esther L. German
Mark Holloway
Beatriz F. Carniel
Mei Ling J. N. Chu
Kayleigh Arp
Elisabeth A. M. Sanders
Daniela M. Ferreira
Debby Bogaert
Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine
description Using a Streptococcus pneumoniae human challenge model, the authors here show that baseline nasal microbiota profiles are associated with pneumococcal acquisition and density, independent of live-attenuated influenza vaccine (LAIV) administration, and with mucosal cytokine responses to LAIV.
format article
author Wouter A. A. de Steenhuijsen Piters
Simon P. Jochems
Elena Mitsi
Jamie Rylance
Sherin Pojar
Elissavet Nikolaou
Esther L. German
Mark Holloway
Beatriz F. Carniel
Mei Ling J. N. Chu
Kayleigh Arp
Elisabeth A. M. Sanders
Daniela M. Ferreira
Debby Bogaert
author_facet Wouter A. A. de Steenhuijsen Piters
Simon P. Jochems
Elena Mitsi
Jamie Rylance
Sherin Pojar
Elissavet Nikolaou
Esther L. German
Mark Holloway
Beatriz F. Carniel
Mei Ling J. N. Chu
Kayleigh Arp
Elisabeth A. M. Sanders
Daniela M. Ferreira
Debby Bogaert
author_sort Wouter A. A. de Steenhuijsen Piters
title Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine
title_short Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine
title_full Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine
title_fullStr Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine
title_full_unstemmed Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine
title_sort interaction between the nasal microbiota and s. pneumoniae in the context of live-attenuated influenza vaccine
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/41664ac4244044f8a670c8b1459330bb
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