Correlation Analysis between Hemoglobin and C-Reactive Protein in Patients Admitted to an Emergency Unit

Anemia and inflammation are common clinical conditions in emergency departments. This study explored a cohort of patients admitted to the emergency department with a particular interest in determining the frequency of anemia and inflammation and the association between hemoglobin (Hb) and C-reactive...

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Autores principales:	Miguel A. Santos-Silva, Nuno Sousa, João Carlos Sousa
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	hemoglobin C-reactive protein emergency correlation Medicine R
Acceso en línea:	https://doaj.org/article/416ccabf25c94331b75eba801e6e266d
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spelling	oai:doaj.org-article:416ccabf25c94331b75eba801e6e266d2021-11-25T18:02:32ZCorrelation Analysis between Hemoglobin and C-Reactive Protein in Patients Admitted to an Emergency Unit10.3390/jcm102254112077-0383https://doaj.org/article/416ccabf25c94331b75eba801e6e266d2021-11-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/22/5411https://doaj.org/toc/2077-0383Anemia and inflammation are common clinical conditions in emergency departments. This study explored a cohort of patients admitted to the emergency department with a particular interest in determining the frequency of anemia and inflammation and the association between hemoglobin (Hb) and C-reactive protein (CRP) concentrations. The study included 125 patients categorized according to their demographic (gender and age) and clinical condition (Hb and CRP concentrations, pathological background, and diagnostic). We found that anemia and inflammation were simultaneously present in 36.0% of the cohort, reaching 67.0% in patients that were subsequently hospitalized. The Hb level was significantly lower in patients with elevated concentration of CRP when compared to individuals with normal CRP levels (11.58 ± 2.23 vs. 13.25 ± 1.80, <i>p</i> = 0.001); furthermore, we found a significantly negative correlation between Hb concentration and the CRP level (rs = −0.42, <i>p</i> < 0.001). The linear regression model applied to the cohort showed that CRP levels explain 15% of Hb variations. The sensitivity of the CRP/Hb ratio (cut-off = 1.32) as a predictor of hospitalization was 80.0%, with a specificity of 68.4% for all patients. These findings confirmed the prevalence of anemia and inflammation and identified a moderate but significant association between Hb and serum CRP in a heterogeneous group of patients admitted to the emergency department.Miguel A. Santos-SilvaNuno SousaJoão Carlos SousaMDPI AGarticlehemoglobinC-reactive proteinemergencycorrelationMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5411, p 5411 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	hemoglobin C-reactive protein emergency correlation Medicine R
spellingShingle	hemoglobin C-reactive protein emergency correlation Medicine R Miguel A. Santos-Silva Nuno Sousa João Carlos Sousa Correlation Analysis between Hemoglobin and C-Reactive Protein in Patients Admitted to an Emergency Unit
description	Anemia and inflammation are common clinical conditions in emergency departments. This study explored a cohort of patients admitted to the emergency department with a particular interest in determining the frequency of anemia and inflammation and the association between hemoglobin (Hb) and C-reactive protein (CRP) concentrations. The study included 125 patients categorized according to their demographic (gender and age) and clinical condition (Hb and CRP concentrations, pathological background, and diagnostic). We found that anemia and inflammation were simultaneously present in 36.0% of the cohort, reaching 67.0% in patients that were subsequently hospitalized. The Hb level was significantly lower in patients with elevated concentration of CRP when compared to individuals with normal CRP levels (11.58 ± 2.23 vs. 13.25 ± 1.80, <i>p</i> = 0.001); furthermore, we found a significantly negative correlation between Hb concentration and the CRP level (rs = −0.42, <i>p</i> < 0.001). The linear regression model applied to the cohort showed that CRP levels explain 15% of Hb variations. The sensitivity of the CRP/Hb ratio (cut-off = 1.32) as a predictor of hospitalization was 80.0%, with a specificity of 68.4% for all patients. These findings confirmed the prevalence of anemia and inflammation and identified a moderate but significant association between Hb and serum CRP in a heterogeneous group of patients admitted to the emergency department.
format	article
author	Miguel A. Santos-Silva Nuno Sousa João Carlos Sousa
author_facet	Miguel A. Santos-Silva Nuno Sousa João Carlos Sousa
author_sort	Miguel A. Santos-Silva
title	Correlation Analysis between Hemoglobin and C-Reactive Protein in Patients Admitted to an Emergency Unit
title_short	Correlation Analysis between Hemoglobin and C-Reactive Protein in Patients Admitted to an Emergency Unit
title_full	Correlation Analysis between Hemoglobin and C-Reactive Protein in Patients Admitted to an Emergency Unit
title_fullStr	Correlation Analysis between Hemoglobin and C-Reactive Protein in Patients Admitted to an Emergency Unit
title_full_unstemmed	Correlation Analysis between Hemoglobin and C-Reactive Protein in Patients Admitted to an Emergency Unit
title_sort	correlation analysis between hemoglobin and c-reactive protein in patients admitted to an emergency unit
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/416ccabf25c94331b75eba801e6e266d
work_keys_str_mv	AT miguelasantossilva correlationanalysisbetweenhemoglobinandcreactiveproteininpatientsadmittedtoanemergencyunit AT nunosousa correlationanalysisbetweenhemoglobinandcreactiveproteininpatientsadmittedtoanemergencyunit AT joaocarlossousa correlationanalysisbetweenhemoglobinandcreactiveproteininpatientsadmittedtoanemergencyunit
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Correlation Analysis between Hemoglobin and C-Reactive Protein in Patients Admitted to an Emergency Unit

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