Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate

Our understanding of how the germline of the parasitic flatworm Schistosoma mansoni develops is limited. Here, the authors use single cell RNAseq and functional genomic analysis of juvenile worms to identify a regulatory program that mediates the fate of germline stem cells between proliferation and...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Pengyang Li, Dania Nanes Sarfati, Yuan Xue, Xi Yu, Alexander J. Tarashansky, Stephen R. Quake, Bo Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4176f353afde4a5ab745c9d925350888
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4176f353afde4a5ab745c9d925350888
record_format	dspace
spelling	oai:doaj.org-article:4176f353afde4a5ab745c9d9253508882021-12-02T13:57:11ZSingle-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate10.1038/s41467-020-20794-w2041-1723https://doaj.org/article/4176f353afde4a5ab745c9d9253508882021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20794-whttps://doaj.org/toc/2041-1723Our understanding of how the germline of the parasitic flatworm Schistosoma mansoni develops is limited. Here, the authors use single cell RNAseq and functional genomic analysis of juvenile worms to identify a regulatory program that mediates the fate of germline stem cells between proliferation and differentiation.Pengyang LiDania Nanes SarfatiYuan XueXi YuAlexander J. TarashanskyStephen R. QuakeBo WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pengyang Li Dania Nanes Sarfati Yuan Xue Xi Yu Alexander J. Tarashansky Stephen R. Quake Bo Wang Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate
description	Our understanding of how the germline of the parasitic flatworm Schistosoma mansoni develops is limited. Here, the authors use single cell RNAseq and functional genomic analysis of juvenile worms to identify a regulatory program that mediates the fate of germline stem cells between proliferation and differentiation.
format	article
author	Pengyang Li Dania Nanes Sarfati Yuan Xue Xi Yu Alexander J. Tarashansky Stephen R. Quake Bo Wang
author_facet	Pengyang Li Dania Nanes Sarfati Yuan Xue Xi Yu Alexander J. Tarashansky Stephen R. Quake Bo Wang
author_sort	Pengyang Li
title	Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate
title_short	Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate
title_full	Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate
title_fullStr	Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate
title_full_unstemmed	Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate
title_sort	single-cell analysis of schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4176f353afde4a5ab745c9d925350888
work_keys_str_mv	AT pengyangli singlecellanalysisofschistosomamansoniidentifiesaconservedgeneticprogramcontrollinggermlinestemcellfate AT daniananessarfati singlecellanalysisofschistosomamansoniidentifiesaconservedgeneticprogramcontrollinggermlinestemcellfate AT yuanxue singlecellanalysisofschistosomamansoniidentifiesaconservedgeneticprogramcontrollinggermlinestemcellfate AT xiyu singlecellanalysisofschistosomamansoniidentifiesaconservedgeneticprogramcontrollinggermlinestemcellfate AT alexanderjtarashansky singlecellanalysisofschistosomamansoniidentifiesaconservedgeneticprogramcontrollinggermlinestemcellfate AT stephenrquake singlecellanalysisofschistosomamansoniidentifiesaconservedgeneticprogramcontrollinggermlinestemcellfate AT bowang singlecellanalysisofschistosomamansoniidentifiesaconservedgeneticprogramcontrollinggermlinestemcellfate
_version_	1718392316758065152

Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate

Ejemplares similares