Migratory Whooper Swans Cygnus cygnus Transmit H5N1 Virus between China and Mongolia: Combination Evidence from Satellite Tracking and Phylogenetics Analysis
Abstract In late 2014, a highly pathogenic avian influenza (hereafter HPAI) H5N1 outbreak infected whooper swans Cygnus cygnus wintering at the Sanmenxia Reservoir area, China, and raised concerns about migratory linkages between wintering and breeding grounds of whooper swans. In this study, 61 swa...
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2018
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oai:doaj.org-article:417816c3878f4f5486e47db2477baae82021-12-02T16:08:13ZMigratory Whooper Swans Cygnus cygnus Transmit H5N1 Virus between China and Mongolia: Combination Evidence from Satellite Tracking and Phylogenetics Analysis10.1038/s41598-018-25291-12045-2322https://doaj.org/article/417816c3878f4f5486e47db2477baae82018-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-25291-1https://doaj.org/toc/2045-2322Abstract In late 2014, a highly pathogenic avian influenza (hereafter HPAI) H5N1 outbreak infected whooper swans Cygnus cygnus wintering at the Sanmenxia Reservoir area, China, and raised concerns about migratory linkages between wintering and breeding grounds of whooper swans. In this study, 61 swans were satellite tracked from 2013 to 2016 to determine the spatial association of their migration routes and H5N1 outbreaks, and 3596 fecal samples were collected along the migration routes for virology testing. Swans departed the wintering grounds and migrated along the Yellow River, and flew over the Yin Mountains in China. The Brownian bridge movement model showed there was a high degree of spatiotemporal overlap between the core use area along the spring migration pathway and historical H5N1 events in China and Mongolia from 2005 to 2015. The H5N1 strain was isolated and phylogenetic analyses confirmed that the HA gene sequence generated is genetically similar to that of the epidemic strain at a previous wintering site (the Sanmenxia Reservoir area) along its flyway. Our results identified a previously unknown migratory link of whooper swans in central China with Mongolia and confirmed that the swans could carry the HPAI H5N1 virus during migration, resulting in long-distance transmission.Shuhong LiWeiyue MengDongping LiuQiqi YangLixia ChenQiang DaiTian MaRuyi GaoWendong RuYunfeng LiPengbo YuJun LuGuogang ZhangHuaiyu TianHongliang ChaiYanbing LiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-9 (2018) |
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Medicine R Science Q Shuhong Li Weiyue Meng Dongping Liu Qiqi Yang Lixia Chen Qiang Dai Tian Ma Ruyi Gao Wendong Ru Yunfeng Li Pengbo Yu Jun Lu Guogang Zhang Huaiyu Tian Hongliang Chai Yanbing Li Migratory Whooper Swans Cygnus cygnus Transmit H5N1 Virus between China and Mongolia: Combination Evidence from Satellite Tracking and Phylogenetics Analysis |
| description |
Abstract In late 2014, a highly pathogenic avian influenza (hereafter HPAI) H5N1 outbreak infected whooper swans Cygnus cygnus wintering at the Sanmenxia Reservoir area, China, and raised concerns about migratory linkages between wintering and breeding grounds of whooper swans. In this study, 61 swans were satellite tracked from 2013 to 2016 to determine the spatial association of their migration routes and H5N1 outbreaks, and 3596 fecal samples were collected along the migration routes for virology testing. Swans departed the wintering grounds and migrated along the Yellow River, and flew over the Yin Mountains in China. The Brownian bridge movement model showed there was a high degree of spatiotemporal overlap between the core use area along the spring migration pathway and historical H5N1 events in China and Mongolia from 2005 to 2015. The H5N1 strain was isolated and phylogenetic analyses confirmed that the HA gene sequence generated is genetically similar to that of the epidemic strain at a previous wintering site (the Sanmenxia Reservoir area) along its flyway. Our results identified a previously unknown migratory link of whooper swans in central China with Mongolia and confirmed that the swans could carry the HPAI H5N1 virus during migration, resulting in long-distance transmission. |
| format |
article |
| author |
Shuhong Li Weiyue Meng Dongping Liu Qiqi Yang Lixia Chen Qiang Dai Tian Ma Ruyi Gao Wendong Ru Yunfeng Li Pengbo Yu Jun Lu Guogang Zhang Huaiyu Tian Hongliang Chai Yanbing Li |
| author_facet |
Shuhong Li Weiyue Meng Dongping Liu Qiqi Yang Lixia Chen Qiang Dai Tian Ma Ruyi Gao Wendong Ru Yunfeng Li Pengbo Yu Jun Lu Guogang Zhang Huaiyu Tian Hongliang Chai Yanbing Li |
| author_sort |
Shuhong Li |
| title |
Migratory Whooper Swans Cygnus cygnus Transmit H5N1 Virus between China and Mongolia: Combination Evidence from Satellite Tracking and Phylogenetics Analysis |
| title_short |
Migratory Whooper Swans Cygnus cygnus Transmit H5N1 Virus between China and Mongolia: Combination Evidence from Satellite Tracking and Phylogenetics Analysis |
| title_full |
Migratory Whooper Swans Cygnus cygnus Transmit H5N1 Virus between China and Mongolia: Combination Evidence from Satellite Tracking and Phylogenetics Analysis |
| title_fullStr |
Migratory Whooper Swans Cygnus cygnus Transmit H5N1 Virus between China and Mongolia: Combination Evidence from Satellite Tracking and Phylogenetics Analysis |
| title_full_unstemmed |
Migratory Whooper Swans Cygnus cygnus Transmit H5N1 Virus between China and Mongolia: Combination Evidence from Satellite Tracking and Phylogenetics Analysis |
| title_sort |
migratory whooper swans cygnus cygnus transmit h5n1 virus between china and mongolia: combination evidence from satellite tracking and phylogenetics analysis |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/417816c3878f4f5486e47db2477baae8 |
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