Morphology of bronchial epithelium in rodent streptozotocin-induced diabetes mellitus

Aim. To study the morphology of bronchial epithelium in a rodent streptozotocin-induced (STZ) diabetes mellitus. Materials and Methods. . Diabetes mellitus was introduced in 47 white Wistar rats aged 5?6 months (body weight 234.0?2.64 g). 43 white Wistar rats of the same age were used as control...

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Autores principales:	Oksana Anatolyevna Pivovarova, Boris Nikitich Mankovsky
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2013
Materias:	streptozotocin-induced diabetes bronchi morphology Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/417d78cc76b34f929cbfcdf85915c710
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spelling	oai:doaj.org-article:417d78cc76b34f929cbfcdf85915c7102021-11-14T09:00:18ZMorphology of bronchial epithelium in rodent streptozotocin-induced diabetes mellitus2072-03512072-037810.14341/DM2013444-48https://doaj.org/article/417d78cc76b34f929cbfcdf85915c7102013-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6258https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To study the morphology of bronchial epithelium in a rodent streptozotocin-induced (STZ) diabetes mellitus. Materials and Methods. . Diabetes mellitus was introduced in 47 white Wistar rats aged 5?6 months (body weight 234.0?2.64 g). 43 white Wistar rats of the same age were used as control subjects (body weight 242.0?2.13). Diabetes was induced by single intraperitoneal injection of STZ (SIGMA, USA) 60 mg/kg in 0.1 M citrate buffer, pH 4.5. Results. A statistically significant decrease in the total epithelial area by 25.9% was observed in the study group, accompanied by a reduction of the supranuclear zone by 22.1% vs. the control group. Conclusion. We found that bronchial mucous membrane in rodents with STZ-induced diabetes mellitus exhibits signs of atrophy and partial loss of mucous production by bronchial secretory cells.Oksana Anatolyevna PivovarovaBoris Nikitich MankovskyEndocrinology Research Centrearticlestreptozotocin-induced diabetesbronchimorphologyNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 16, Iss 4, Pp 44-48 (2013)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	streptozotocin-induced diabetes bronchi morphology Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	streptozotocin-induced diabetes bronchi morphology Nutritional diseases. Deficiency diseases RC620-627 Oksana Anatolyevna Pivovarova Boris Nikitich Mankovsky Morphology of bronchial epithelium in rodent streptozotocin-induced diabetes mellitus
description	Aim. To study the morphology of bronchial epithelium in a rodent streptozotocin-induced (STZ) diabetes mellitus. Materials and Methods. . Diabetes mellitus was introduced in 47 white Wistar rats aged 5?6 months (body weight 234.0?2.64 g). 43 white Wistar rats of the same age were used as control subjects (body weight 242.0?2.13). Diabetes was induced by single intraperitoneal injection of STZ (SIGMA, USA) 60 mg/kg in 0.1 M citrate buffer, pH 4.5. Results. A statistically significant decrease in the total epithelial area by 25.9% was observed in the study group, accompanied by a reduction of the supranuclear zone by 22.1% vs. the control group. Conclusion. We found that bronchial mucous membrane in rodents with STZ-induced diabetes mellitus exhibits signs of atrophy and partial loss of mucous production by bronchial secretory cells.
format	article
author	Oksana Anatolyevna Pivovarova Boris Nikitich Mankovsky
author_facet	Oksana Anatolyevna Pivovarova Boris Nikitich Mankovsky
author_sort	Oksana Anatolyevna Pivovarova
title	Morphology of bronchial epithelium in rodent streptozotocin-induced diabetes mellitus
title_short	Morphology of bronchial epithelium in rodent streptozotocin-induced diabetes mellitus
title_full	Morphology of bronchial epithelium in rodent streptozotocin-induced diabetes mellitus
title_fullStr	Morphology of bronchial epithelium in rodent streptozotocin-induced diabetes mellitus
title_full_unstemmed	Morphology of bronchial epithelium in rodent streptozotocin-induced diabetes mellitus
title_sort	morphology of bronchial epithelium in rodent streptozotocin-induced diabetes mellitus
publisher	Endocrinology Research Centre
publishDate	2013
url	https://doaj.org/article/417d78cc76b34f929cbfcdf85915c710
work_keys_str_mv	AT oksanaanatolyevnapivovarova morphologyofbronchialepitheliuminrodentstreptozotocininduceddiabetesmellitus AT borisnikitichmankovsky morphologyofbronchialepitheliuminrodentstreptozotocininduceddiabetesmellitus
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Morphology of bronchial epithelium in rodent streptozotocin-induced diabetes mellitus

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