Retinal Microvasculature Changes After Repair of Macula-off Retinal Detachment Assessed with Optical Coherence Tomography Angiography
K Matthew McKay,1,* Filippos Vingopoulos,1,* Jay C Wang,1 Thanos D Papakostas,1,2 Rebecca F Silverman,1 Anna Marmalidou,1 Inês Lains,1 Dean Eliott,1 Demetrios G Vavvas,1 Leo A Kim,1 David M Wu,1 John B Miller1 1Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
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Dove Medical Press
2020
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/4181241af06a444b97100dbc1379e6c3 |
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| Sumario: | K Matthew McKay,1,* Filippos Vingopoulos,1,* Jay C Wang,1 Thanos D Papakostas,1,2 Rebecca F Silverman,1 Anna Marmalidou,1 Inês Lains,1 Dean Eliott,1 Demetrios G Vavvas,1 Leo A Kim,1 David M Wu,1 John B Miller1 1Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA; 2Retina Service, Weill Cornell Medical College, New York, NY, USA*These authors contributed equally to this workCorrespondence: John B MillerRetina Service, Massachusetts Eye and Ear, Harvard Medical School, 243 Charles St, Boston, MA 02114 Tel +1 (617) 573-3750Fax +1 (617) 573-3698Email john_miller@meei.harvard.eduObjective: To characterize the microvascular retinal changes after repair of macula-off rhegmatogenous retinal detachment (RRD) using optical coherence tomography angiography (OCT-A).Patients and Methods: A retrospective review of patients who underwent repair of macula-off RRD. Fellow unaffected eyes were used as controls. Post-operative OCT-A allowed comparison of vessel density (VD) and foveal avascular zone (FAZ) area in the superficial and deep retinal capillary plexus (DCP) as well as VD in the choriocapillaris layer.Results: Seventeen eyes of 17 RRD patients were included in the final analysis. There was a reduction in VD of the deep retinal capillary plexus in affected eyes compared to fellow eyes (p = 0.046). RRD eyes with reduced VD in DCP compared with their fellow control eyes had worse visual acuity after repair compared to those without (p = 0.032). No significant microvasculature changes were detected in the FAZ area and VD in the superficial capillary plexus and choriocapillaris compared to fellow eyes.Conclusion: In macula-off RRD eyes, significant microvascular changes were detected in the DCP using OCT-A even after successful anatomical repair. Decreased VD in the DCP compared to the fellow healthy eyes was correlated with worse visual acuity.Keywords: microvascular changes, OCT-angiography, macula-off retinal detachment |
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