Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series

Abstract Background Rarely, Malassezia otitis presents as a painful, erosive otitis with an otic discharge containing Malassezia and neutrophils on cytology. There are no published reports of this type of suppurative Malassezia otitis (SMO). The role of Malassezia hypersensitivity in otitis is still...

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Autores principales:	Tania C. Nunes Rodrigues, Sophie I. Vandenabeele
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Malassezia hypersensitivity suppurative otitis inflammation canine Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/4187f175c99c4c678dcd2d5a70e83166
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spelling	oai:doaj.org-article:4187f175c99c4c678dcd2d5a70e831662021-11-21T12:25:53ZPilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series10.1186/s12917-021-03066-71746-6148https://doaj.org/article/4187f175c99c4c678dcd2d5a70e831662021-11-01T00:00:00Zhttps://doi.org/10.1186/s12917-021-03066-7https://doaj.org/toc/1746-6148Abstract Background Rarely, Malassezia otitis presents as a painful, erosive otitis with an otic discharge containing Malassezia and neutrophils on cytology. There are no published reports of this type of suppurative Malassezia otitis (SMO). The role of Malassezia hypersensitivity in otitis is still unknown, and no association has been demonstrated with SMO. We compared Malassezia IgE levels, intradermal test and histology changes in SMO dogs with the more conventional Malassezia otitis (MO) presentation. Results Three dogs (case 1, case 2 and case 3) were diagnosed with SMO, one dog (case 4) was diagnosed with unilateral MO and unilateral SMO, and one dog (case 5) was diagnosed with MO. Only one case (case 4) with SMO/MO had a positive Intradermal Allergy Test (IDAT) and elevated IgE levels for Malassezia. Histopathology findings from SMO revealed: interface dermatitis (case 1 and 3), lymphocytic dermatitis (case 2) and chronic hyperplastic eosinophilic and lymphoplasmacytic dermatitis (case 4). Histopathology findings from MO showed perivascular dermatitis (case 4 and 5). All the cases were treated successfully. Conclusions SMO presents with a distinct clinical phenotype in comparison with conventional MO. No consistent aetiology could be isolated. In these clinical cases it is possible that previous treatments could have influenced the results. More research is needed to understand the possible aetiologies and the pathogenesis of SMO.Tania C. Nunes RodriguesSophie I. VandenabeeleBMCarticleMalasseziahypersensitivitysuppurativeotitisinflammationcanineVeterinary medicineSF600-1100ENBMC Veterinary Research, Vol 17, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Malassezia hypersensitivity suppurative otitis inflammation canine Veterinary medicine SF600-1100
spellingShingle	Malassezia hypersensitivity suppurative otitis inflammation canine Veterinary medicine SF600-1100 Tania C. Nunes Rodrigues Sophie I. Vandenabeele Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series
description	Abstract Background Rarely, Malassezia otitis presents as a painful, erosive otitis with an otic discharge containing Malassezia and neutrophils on cytology. There are no published reports of this type of suppurative Malassezia otitis (SMO). The role of Malassezia hypersensitivity in otitis is still unknown, and no association has been demonstrated with SMO. We compared Malassezia IgE levels, intradermal test and histology changes in SMO dogs with the more conventional Malassezia otitis (MO) presentation. Results Three dogs (case 1, case 2 and case 3) were diagnosed with SMO, one dog (case 4) was diagnosed with unilateral MO and unilateral SMO, and one dog (case 5) was diagnosed with MO. Only one case (case 4) with SMO/MO had a positive Intradermal Allergy Test (IDAT) and elevated IgE levels for Malassezia. Histopathology findings from SMO revealed: interface dermatitis (case 1 and 3), lymphocytic dermatitis (case 2) and chronic hyperplastic eosinophilic and lymphoplasmacytic dermatitis (case 4). Histopathology findings from MO showed perivascular dermatitis (case 4 and 5). All the cases were treated successfully. Conclusions SMO presents with a distinct clinical phenotype in comparison with conventional MO. No consistent aetiology could be isolated. In these clinical cases it is possible that previous treatments could have influenced the results. More research is needed to understand the possible aetiologies and the pathogenesis of SMO.
format	article
author	Tania C. Nunes Rodrigues Sophie I. Vandenabeele
author_facet	Tania C. Nunes Rodrigues Sophie I. Vandenabeele
author_sort	Tania C. Nunes Rodrigues
title	Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series
title_short	Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series
title_full	Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series
title_fullStr	Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series
title_full_unstemmed	Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series
title_sort	pilot study of dogs with suppurative and non-suppurative malassezia otitis: a case series
publisher	BMC
publishDate	2021
url	https://doaj.org/article/4187f175c99c4c678dcd2d5a70e83166
work_keys_str_mv	AT taniacnunesrodrigues pilotstudyofdogswithsuppurativeandnonsuppurativemalasseziaotitisacaseseries AT sophieivandenabeele pilotstudyofdogswithsuppurativeandnonsuppurativemalasseziaotitisacaseseries
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Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series

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