Differential regulation of cysteinyl leukotriene receptor signaling by protein kinase C in human mast cells.

Cysteinyl leukotrienes (cys-LTs) are a group of lipid mediators that are potent bronchoconstrictors, powerful inducers of vascular leakage and potentiators of airway hyperresponsiveness. Cys-LTs play an essential role in asthma and are synthesized as well as activated in mast cells (MCs). Cys-LTs re...

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Autores principales: Vinay Kondeti, Ernest Duah, Nosayba Al-Azzam, Charles K Thodeti, Joshua A Boyce, Sailaja Paruchuri
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/418e8f2ea42e4812924527b50897c7ea
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