A processive phosphorylation circuit with multiple kinase inputs and mutually diversional routes controls G1/S decision
The decision of whether and when a cell divides is tightly controlled. Here, the authors show in yeast that there is a multi-step competition between different phosphorylation states and sites in the S phase CDK-Sic1 complex, which controls Sic1 degradation and coordinates the precise timing of the...
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Autores principales: | Rainis Venta, Ervin Valk, Mihkel Örd, Oleg Košik, Kaur Pääbo, Artemi Maljavin, Rait Kivi, Ilona Faustova, Nastassia Shtaida, Martin Lepiku, Kaidi Möll, Andreas Doncic, Mardo Kõivomägi, Mart Loog |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/4193f9a7643148afba8fdec5cd394703 |
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