MoVE identifies metabolic valves to switch between phenotypic states

Interventions in metabolic networks can improve microbes for chemical production. Here, the authors develop a tool to identify metabolic valves that can decouple growth and production to systematically improve the rate and yield of biochemical production processes.

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Autores principales: Naveen Venayak, Axel von Kamp, Steffen Klamt, Radhakrishnan Mahadevan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/419c442cda8b441abf5e001a402384c7
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spelling oai:doaj.org-article:419c442cda8b441abf5e001a402384c72021-12-02T15:33:46ZMoVE identifies metabolic valves to switch between phenotypic states10.1038/s41467-018-07719-42041-1723https://doaj.org/article/419c442cda8b441abf5e001a402384c72018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07719-4https://doaj.org/toc/2041-1723Interventions in metabolic networks can improve microbes for chemical production. Here, the authors develop a tool to identify metabolic valves that can decouple growth and production to systematically improve the rate and yield of biochemical production processes.Naveen VenayakAxel von KampSteffen KlamtRadhakrishnan MahadevanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Naveen Venayak
Axel von Kamp
Steffen Klamt
Radhakrishnan Mahadevan
MoVE identifies metabolic valves to switch between phenotypic states
description Interventions in metabolic networks can improve microbes for chemical production. Here, the authors develop a tool to identify metabolic valves that can decouple growth and production to systematically improve the rate and yield of biochemical production processes.
format article
author Naveen Venayak
Axel von Kamp
Steffen Klamt
Radhakrishnan Mahadevan
author_facet Naveen Venayak
Axel von Kamp
Steffen Klamt
Radhakrishnan Mahadevan
author_sort Naveen Venayak
title MoVE identifies metabolic valves to switch between phenotypic states
title_short MoVE identifies metabolic valves to switch between phenotypic states
title_full MoVE identifies metabolic valves to switch between phenotypic states
title_fullStr MoVE identifies metabolic valves to switch between phenotypic states
title_full_unstemmed MoVE identifies metabolic valves to switch between phenotypic states
title_sort move identifies metabolic valves to switch between phenotypic states
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/419c442cda8b441abf5e001a402384c7
work_keys_str_mv AT naveenvenayak moveidentifiesmetabolicvalvestoswitchbetweenphenotypicstates
AT axelvonkamp moveidentifiesmetabolicvalvestoswitchbetweenphenotypicstates
AT steffenklamt moveidentifiesmetabolicvalvestoswitchbetweenphenotypicstates
AT radhakrishnanmahadevan moveidentifiesmetabolicvalvestoswitchbetweenphenotypicstates
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