MoVE identifies metabolic valves to switch between phenotypic states
Interventions in metabolic networks can improve microbes for chemical production. Here, the authors develop a tool to identify metabolic valves that can decouple growth and production to systematically improve the rate and yield of biochemical production processes.
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Nature Portfolio
2018
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oai:doaj.org-article:419c442cda8b441abf5e001a402384c72021-12-02T15:33:46ZMoVE identifies metabolic valves to switch between phenotypic states10.1038/s41467-018-07719-42041-1723https://doaj.org/article/419c442cda8b441abf5e001a402384c72018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07719-4https://doaj.org/toc/2041-1723Interventions in metabolic networks can improve microbes for chemical production. Here, the authors develop a tool to identify metabolic valves that can decouple growth and production to systematically improve the rate and yield of biochemical production processes.Naveen VenayakAxel von KampSteffen KlamtRadhakrishnan MahadevanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Naveen Venayak Axel von Kamp Steffen Klamt Radhakrishnan Mahadevan MoVE identifies metabolic valves to switch between phenotypic states |
description |
Interventions in metabolic networks can improve microbes for chemical production. Here, the authors develop a tool to identify metabolic valves that can decouple growth and production to systematically improve the rate and yield of biochemical production processes. |
format |
article |
author |
Naveen Venayak Axel von Kamp Steffen Klamt Radhakrishnan Mahadevan |
author_facet |
Naveen Venayak Axel von Kamp Steffen Klamt Radhakrishnan Mahadevan |
author_sort |
Naveen Venayak |
title |
MoVE identifies metabolic valves to switch between phenotypic states |
title_short |
MoVE identifies metabolic valves to switch between phenotypic states |
title_full |
MoVE identifies metabolic valves to switch between phenotypic states |
title_fullStr |
MoVE identifies metabolic valves to switch between phenotypic states |
title_full_unstemmed |
MoVE identifies metabolic valves to switch between phenotypic states |
title_sort |
move identifies metabolic valves to switch between phenotypic states |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/419c442cda8b441abf5e001a402384c7 |
work_keys_str_mv |
AT naveenvenayak moveidentifiesmetabolicvalvestoswitchbetweenphenotypicstates AT axelvonkamp moveidentifiesmetabolicvalvestoswitchbetweenphenotypicstates AT steffenklamt moveidentifiesmetabolicvalvestoswitchbetweenphenotypicstates AT radhakrishnanmahadevan moveidentifiesmetabolicvalvestoswitchbetweenphenotypicstates |
_version_ |
1718387019481088000 |