Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression

The role of long non-coding RNAs (lncRNAs) in metastatic colorectal cancer (mCRC) and treatment resistance is unclear. Here, the authors use transcriptome sequencing of matched normal, primary, and metastatic CRC tissues to discover and validate that lncRNA RAMS11 promotes metastasis and resistance...

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Autores principales:	Jessica M. Silva-Fisher, Ha X. Dang, Nicole M. White, Matthew S. Strand, Bradley A. Krasnick, Emily B. Rozycki, Gejae G. L. Jeffers, Julie G. Grossman, Maureen K. Highkin, Cynthia Tang, Christopher R. Cabanski, Abdallah Eteleeb, Jacqueline Mudd, S. Peter Goedegebuure, Jingqin Luo, Elaine R. Mardis, Richard K. Wilson, Timothy J. Ley, Albert C. Lockhart, Ryan C. Fields, Christopher A. Maher
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/419e0097c4524d55a96202eb846d0823
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spelling	oai:doaj.org-article:419e0097c4524d55a96202eb846d08232021-12-02T14:40:29ZLong non-coding RNA RAMS11 promotes metastatic colorectal cancer progression10.1038/s41467-020-15547-82041-1723https://doaj.org/article/419e0097c4524d55a96202eb846d08232020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15547-8https://doaj.org/toc/2041-1723The role of long non-coding RNAs (lncRNAs) in metastatic colorectal cancer (mCRC) and treatment resistance is unclear. Here, the authors use transcriptome sequencing of matched normal, primary, and metastatic CRC tissues to discover and validate that lncRNA RAMS11 promotes metastasis and resistance to topoisomerase inhibitors in mCRC.Jessica M. Silva-FisherHa X. DangNicole M. WhiteMatthew S. StrandBradley A. KrasnickEmily B. RozyckiGejae G. L. JeffersJulie G. GrossmanMaureen K. HighkinCynthia TangChristopher R. CabanskiAbdallah EteleebJacqueline MuddS. Peter GoedegebuureJingqin LuoElaine R. MardisRichard K. WilsonTimothy J. LeyAlbert C. LockhartRyan C. FieldsChristopher A. MaherNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jessica M. Silva-Fisher Ha X. Dang Nicole M. White Matthew S. Strand Bradley A. Krasnick Emily B. Rozycki Gejae G. L. Jeffers Julie G. Grossman Maureen K. Highkin Cynthia Tang Christopher R. Cabanski Abdallah Eteleeb Jacqueline Mudd S. Peter Goedegebuure Jingqin Luo Elaine R. Mardis Richard K. Wilson Timothy J. Ley Albert C. Lockhart Ryan C. Fields Christopher A. Maher Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression
description	The role of long non-coding RNAs (lncRNAs) in metastatic colorectal cancer (mCRC) and treatment resistance is unclear. Here, the authors use transcriptome sequencing of matched normal, primary, and metastatic CRC tissues to discover and validate that lncRNA RAMS11 promotes metastasis and resistance to topoisomerase inhibitors in mCRC.
format	article
author	Jessica M. Silva-Fisher Ha X. Dang Nicole M. White Matthew S. Strand Bradley A. Krasnick Emily B. Rozycki Gejae G. L. Jeffers Julie G. Grossman Maureen K. Highkin Cynthia Tang Christopher R. Cabanski Abdallah Eteleeb Jacqueline Mudd S. Peter Goedegebuure Jingqin Luo Elaine R. Mardis Richard K. Wilson Timothy J. Ley Albert C. Lockhart Ryan C. Fields Christopher A. Maher
author_facet	Jessica M. Silva-Fisher Ha X. Dang Nicole M. White Matthew S. Strand Bradley A. Krasnick Emily B. Rozycki Gejae G. L. Jeffers Julie G. Grossman Maureen K. Highkin Cynthia Tang Christopher R. Cabanski Abdallah Eteleeb Jacqueline Mudd S. Peter Goedegebuure Jingqin Luo Elaine R. Mardis Richard K. Wilson Timothy J. Ley Albert C. Lockhart Ryan C. Fields Christopher A. Maher
author_sort	Jessica M. Silva-Fisher
title	Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression
title_short	Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression
title_full	Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression
title_fullStr	Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression
title_full_unstemmed	Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression
title_sort	long non-coding rna rams11 promotes metastatic colorectal cancer progression
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/419e0097c4524d55a96202eb846d0823
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Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression

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