Porphyromonas gingivalis bypasses epithelial barrier and modulates fibroblastic inflammatory response in an in vitro 3D spheroid model
Abstract Porphyromonas gingivalis-induced inflammatory effects are mostly investigated in monolayer cultured cells. The aim of this study was to develop a 3D spheroid model of gingiva to take into account epithelio-fibroblastic interactions. Human gingival epithelial cells (ECs) and human oral fibro...
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Autores principales: | Isaac Maximiliano Bugueno, Fareeha Batool, Laetitia Keller, Sabine Kuchler-Bopp, Nadia Benkirane-Jessel, Olivier Huck |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/41a1965e25ef41a7941e0b7e8bd6c376 |
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