Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization

Nanoclays have been used in composites and for drug delivery but have suffered from a trade-off in properties when used for both. Here the authors report on the use of bisphosphonate interactions with nanoclay edges to made drug loaded composites without compromising materials properties or drug loa...

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Autores principales:	Yang-Hee Kim, Xia Yang, Liyang Shi, Stuart A. Lanham, Jons Hilborn, Richard O. C. Oreffo, Dmitri Ossipov, Jonathan I. Dawson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/41a86af5e4484cad8948fc2edb37c766
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spelling	oai:doaj.org-article:41a86af5e4484cad8948fc2edb37c7662021-12-02T15:34:14ZBisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization10.1038/s41467-020-15152-92041-1723https://doaj.org/article/41a86af5e4484cad8948fc2edb37c7662020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15152-9https://doaj.org/toc/2041-1723Nanoclays have been used in composites and for drug delivery but have suffered from a trade-off in properties when used for both. Here the authors report on the use of bisphosphonate interactions with nanoclay edges to made drug loaded composites without compromising materials properties or drug loading.Yang-Hee KimXia YangLiyang ShiStuart A. LanhamJons HilbornRichard O. C. OreffoDmitri OssipovJonathan I. DawsonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yang-Hee Kim Xia Yang Liyang Shi Stuart A. Lanham Jons Hilborn Richard O. C. Oreffo Dmitri Ossipov Jonathan I. Dawson Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization
description	Nanoclays have been used in composites and for drug delivery but have suffered from a trade-off in properties when used for both. Here the authors report on the use of bisphosphonate interactions with nanoclay edges to made drug loaded composites without compromising materials properties or drug loading.
format	article
author	Yang-Hee Kim Xia Yang Liyang Shi Stuart A. Lanham Jons Hilborn Richard O. C. Oreffo Dmitri Ossipov Jonathan I. Dawson
author_facet	Yang-Hee Kim Xia Yang Liyang Shi Stuart A. Lanham Jons Hilborn Richard O. C. Oreffo Dmitri Ossipov Jonathan I. Dawson
author_sort	Yang-Hee Kim
title	Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization
title_short	Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization
title_full	Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization
title_fullStr	Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization
title_full_unstemmed	Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization
title_sort	bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/41a86af5e4484cad8948fc2edb37c766
work_keys_str_mv	AT yangheekim bisphosphonatenanoclayedgesiteinteractionsfacilitatehydrogelselfassemblyandsustainedgrowthfactorlocalization AT xiayang bisphosphonatenanoclayedgesiteinteractionsfacilitatehydrogelselfassemblyandsustainedgrowthfactorlocalization AT liyangshi bisphosphonatenanoclayedgesiteinteractionsfacilitatehydrogelselfassemblyandsustainedgrowthfactorlocalization AT stuartalanham bisphosphonatenanoclayedgesiteinteractionsfacilitatehydrogelselfassemblyandsustainedgrowthfactorlocalization AT jonshilborn bisphosphonatenanoclayedgesiteinteractionsfacilitatehydrogelselfassemblyandsustainedgrowthfactorlocalization AT richardocoreffo bisphosphonatenanoclayedgesiteinteractionsfacilitatehydrogelselfassemblyandsustainedgrowthfactorlocalization AT dmitriossipov bisphosphonatenanoclayedgesiteinteractionsfacilitatehydrogelselfassemblyandsustainedgrowthfactorlocalization AT jonathanidawson bisphosphonatenanoclayedgesiteinteractionsfacilitatehydrogelselfassemblyandsustainedgrowthfactorlocalization
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Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization

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