Pharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecuador

Abstract. Sarmiento-Tomalá GM, Miranda-Martínez M, Chóez-Guaranda IA, Gutiérrez-Gaitén YI, Delgado-Hernández R, Carrillo-Lavid G. 2020. Pharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecua...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Migdalia Miranda-Martínez, GLENDA MARCELA SARMIENTO-TOMALÁ, IVÁN ANDRÉS CHÓEZ-GUARANDA, YAMILET IRENE GUTIÉRREZ-GAITÉN, RENÉ DELGADO-HERNÁNDEZ, GABRIELA CARRILLO-LAVID
Formato:	article
Lenguaje:	EN
Publicado:	MBI & UNS Solo 2020
Materias:	chemical composition, gas chromatography-mass spectrometry, pharmacognosy, physicochemical parameters Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/41acc38a22694e87b6d9cd8618f72dc5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:41acc38a22694e87b6d9cd8618f72dc5
record_format	dspace
spelling	oai:doaj.org-article:41acc38a22694e87b6d9cd8618f72dc52021-11-22T00:51:08ZPharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecuador1412-033X2085-472210.13057/biodiv/d211040https://doaj.org/article/41acc38a22694e87b6d9cd8618f72dc52020-09-01T00:00:00Zhttps://smujo.id/biodiv/article/view/6642https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Abstract. Sarmiento-Tomalá GM, Miranda-Martínez M, Chóez-Guaranda IA, Gutiérrez-Gaitén YI, Delgado-Hernández R, Carrillo-Lavid G. 2020. Pharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecuador. Biodiversitas 21: 4755-4763. Among the cultivated and/or native plant species of Ecuador, are those belonging to Malvaceae. Of these, the most traditionally used are Malva pseudolavatera Webb & Berthel. and Malva sylvestris L., which are grown and sold in indigenous markets. Various articles have been published for M. sylvestris about its chemical composition and pharmacological properties; however, M. pseudolavatera lacks references and is the most commercialized in Ecuador. Therefore, this work sets the following objective: To carry out a comparative study of the pharmacognostic, chemical and mucolytic activity of the species M. pseudolavatera and M. sylvestris. The species studied were collected in the province of Chimborazo. Extracts were obtained with different solvents: water, hexane and 80% ethanol. The aqueous extract was used to determine the mucolytic activity; the hexane and alcoholic extracts were analyzed by the coupled gas chromatography-mass spectrometry system. It was found that M. pseudolavatera has a very similar chemical composition to M. sylvestris; The presence of fatty acids, di and triterpenoids, phytosterols and abundant amino acids was detected. Both species showed an important mucolytic effect, the activity of M. pseudolavatera being higher than the highest doses tested. These studies provide scientific data that allow demonstrating the high potentiality of extracts from the leaves of two Malva species as sources of plant material for possible research and development of phytotherapeutic products with mucolytic and gastroprotective activity in correspondence with their uses in traditional Ecuadorian herbal medicine.Migdalia Miranda-MartínezGLENDA MARCELA SARMIENTO-TOMALÁIVÁN ANDRÉS CHÓEZ-GUARANDAYAMILET IRENE GUTIÉRREZ-GAITÉNRENÉ DELGADO-HERNÁNDEZGABRIELA CARRILLO-LAVIDMBI & UNS Soloarticlechemical composition, gas chromatography-mass spectrometry, pharmacognosy, physicochemical parametersBiology (General)QH301-705.5ENBiodiversitas, Vol 21, Iss 10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	chemical composition, gas chromatography-mass spectrometry, pharmacognosy, physicochemical parameters Biology (General) QH301-705.5
spellingShingle	chemical composition, gas chromatography-mass spectrometry, pharmacognosy, physicochemical parameters Biology (General) QH301-705.5 Migdalia Miranda-Martínez GLENDA MARCELA SARMIENTO-TOMALÁ IVÁN ANDRÉS CHÓEZ-GUARANDA YAMILET IRENE GUTIÉRREZ-GAITÉN RENÉ DELGADO-HERNÁNDEZ GABRIELA CARRILLO-LAVID Pharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecuador
description	Abstract. Sarmiento-Tomalá GM, Miranda-Martínez M, Chóez-Guaranda IA, Gutiérrez-Gaitén YI, Delgado-Hernández R, Carrillo-Lavid G. 2020. Pharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecuador. Biodiversitas 21: 4755-4763. Among the cultivated and/or native plant species of Ecuador, are those belonging to Malvaceae. Of these, the most traditionally used are Malva pseudolavatera Webb & Berthel. and Malva sylvestris L., which are grown and sold in indigenous markets. Various articles have been published for M. sylvestris about its chemical composition and pharmacological properties; however, M. pseudolavatera lacks references and is the most commercialized in Ecuador. Therefore, this work sets the following objective: To carry out a comparative study of the pharmacognostic, chemical and mucolytic activity of the species M. pseudolavatera and M. sylvestris. The species studied were collected in the province of Chimborazo. Extracts were obtained with different solvents: water, hexane and 80% ethanol. The aqueous extract was used to determine the mucolytic activity; the hexane and alcoholic extracts were analyzed by the coupled gas chromatography-mass spectrometry system. It was found that M. pseudolavatera has a very similar chemical composition to M. sylvestris; The presence of fatty acids, di and triterpenoids, phytosterols and abundant amino acids was detected. Both species showed an important mucolytic effect, the activity of M. pseudolavatera being higher than the highest doses tested. These studies provide scientific data that allow demonstrating the high potentiality of extracts from the leaves of two Malva species as sources of plant material for possible research and development of phytotherapeutic products with mucolytic and gastroprotective activity in correspondence with their uses in traditional Ecuadorian herbal medicine.
format	article
author	Migdalia Miranda-Martínez GLENDA MARCELA SARMIENTO-TOMALÁ IVÁN ANDRÉS CHÓEZ-GUARANDA YAMILET IRENE GUTIÉRREZ-GAITÉN RENÉ DELGADO-HERNÁNDEZ GABRIELA CARRILLO-LAVID
author_facet	Migdalia Miranda-Martínez GLENDA MARCELA SARMIENTO-TOMALÁ IVÁN ANDRÉS CHÓEZ-GUARANDA YAMILET IRENE GUTIÉRREZ-GAITÉN RENÉ DELGADO-HERNÁNDEZ GABRIELA CARRILLO-LAVID
author_sort	Migdalia Miranda-Martínez
title	Pharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecuador
title_short	Pharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecuador
title_full	Pharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecuador
title_fullStr	Pharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecuador
title_full_unstemmed	Pharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecuador
title_sort	pharmacognostic, chemical and mucolytic activity study of malva pseudolavatera webb & berthel. and malva sylvestris l. (malvaceae) leaf extracts, grown in ecuador
publisher	MBI & UNS Solo
publishDate	2020
url	https://doaj.org/article/41acc38a22694e87b6d9cd8618f72dc5
work_keys_str_mv	AT migdaliamirandamartinez pharmacognosticchemicalandmucolyticactivitystudyofmalvapseudolavaterawebbberthelandmalvasylvestrislmalvaceaeleafextractsgrowninecuador AT glendamarcelasarmientotomala pharmacognosticchemicalandmucolyticactivitystudyofmalvapseudolavaterawebbberthelandmalvasylvestrislmalvaceaeleafextractsgrowninecuador AT ivanandreschoezguaranda pharmacognosticchemicalandmucolyticactivitystudyofmalvapseudolavaterawebbberthelandmalvasylvestrislmalvaceaeleafextractsgrowninecuador AT yamiletirenegutierrezgaiten pharmacognosticchemicalandmucolyticactivitystudyofmalvapseudolavaterawebbberthelandmalvasylvestrislmalvaceaeleafextractsgrowninecuador AT renedelgadohernandez pharmacognosticchemicalandmucolyticactivitystudyofmalvapseudolavaterawebbberthelandmalvasylvestrislmalvaceaeleafextractsgrowninecuador AT gabrielacarrillolavid pharmacognosticchemicalandmucolyticactivitystudyofmalvapseudolavaterawebbberthelandmalvasylvestrislmalvaceaeleafextractsgrowninecuador
_version_	1718418456008720384

Pharmacognostic, chemical and mucolytic activity study of Malva pseudolavatera Webb & Berthel. and Malva sylvestris L. (Malvaceae) leaf extracts, grown in Ecuador

Ejemplares similares