EFFECT OF CARICA PAPAYA L LEAF ON MENSTRUAL PAIN AND PROSTAGLANDIN LEVEL IN ADOLESCENT WITH PRIMARY DYSMENORRHEA: A TRUE EXPERIMENT

Background: Primary dysmenorrhea occurs because of the excessive amount of prostaglandins in the blood. Papaya leaf extract is considered to be able to reduce prostaglandin and menstrual pain. Objective: This study aims to prove that papaya leaf extract (Carica Papaya L.) can decrease the level of...

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Autores principales:	Siska Nurul Abidah, Soeharyo Hadisaputro, Runjati, Syarief Thaufik Hidayat, Ari Suwondo, Donny Kristanto Mulyantoro
Formato:	article
Lenguaje:	EN
Publicado:	Belitung Raya Foundation 2017
Materias:	Carica Papaya L. primary dysmenorrhea menstrual pain prostaglandin level Nursing RT1-120
Acceso en línea:	https://doaj.org/article/41b844fd031c404c98fd6ba14684d7b5
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spelling	oai:doaj.org-article:41b844fd031c404c98fd6ba14684d7b52021-12-02T12:27:43ZEFFECT OF CARICA PAPAYA L LEAF ON MENSTRUAL PAIN AND PROSTAGLANDIN LEVEL IN ADOLESCENT WITH PRIMARY DYSMENORRHEA: A TRUE EXPERIMENT2477-40732477-4073https://doaj.org/article/41b844fd031c404c98fd6ba14684d7b52017-07-01T00:00:00Zhttp://belitungraya.org/BRP/index.php/bnj/article/view/96https://doaj.org/toc/2477-4073https://doaj.org/toc/2477-4073Background: Primary dysmenorrhea occurs because of the excessive amount of prostaglandins in the blood. Papaya leaf extract is considered to be able to reduce prostaglandin and menstrual pain. Objective: This study aims to prove that papaya leaf extract (Carica Papaya L.) can decrease the level of menstrual pain and prostaglandin levels in primary dysmenorrhea. Methods: A true experimental study with randomized pretest posttest control group design. There were 32 samples recruited using simple random sampling, with 16 each assigned to an experiment and control group. Numerical Rating Scale (NRS) was used to measure menstrual pain, and the level of prostaglandin was measured using the enzyme-linked immunosorbent assay (ELISA) method. Independent t-test and paired t-test were performed for data analysis. Results: There was statistically significant differencec of menstrual pain and prostaglandin level before and after intervention with p-value 0.000 (<0.005), which indiciated that papaya leaf extract had a significant effect on reducing menstrual pain. The decrease of menstrual pain in the experimental group was -3.375 and in the control group was -3.438; while the decrease of prostaglandin level in the experimental group was -56.971 and in the control group was -57.557. Conclusion: Provision of papaya leaf extract (Carica Papaya L.) significantly decreased the level of menstrual pain and prostaglandin levels in primary dysmenorrhea. Papaya leaf extract can be used as a safe and effective herbal medicine for primary dysmenorrhoea which has almost the same efficacy as mefenamic acid. Siska Nurul AbidahSoeharyo HadisaputroRunjatiSyarief Thaufik HidayatAri SuwondoDonny Kristanto MulyantoroBelitung Raya FoundationarticleCarica Papaya L.primary dysmenorrheamenstrual painprostaglandin levelNursingRT1-120ENBelitung Nursing Journal, Vol 3, Iss 3, Pp 198-204 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Carica Papaya L. primary dysmenorrhea menstrual pain prostaglandin level Nursing RT1-120
spellingShingle	Carica Papaya L. primary dysmenorrhea menstrual pain prostaglandin level Nursing RT1-120 Siska Nurul Abidah Soeharyo Hadisaputro Runjati Syarief Thaufik Hidayat Ari Suwondo Donny Kristanto Mulyantoro EFFECT OF CARICA PAPAYA L LEAF ON MENSTRUAL PAIN AND PROSTAGLANDIN LEVEL IN ADOLESCENT WITH PRIMARY DYSMENORRHEA: A TRUE EXPERIMENT
description	Background: Primary dysmenorrhea occurs because of the excessive amount of prostaglandins in the blood. Papaya leaf extract is considered to be able to reduce prostaglandin and menstrual pain. Objective: This study aims to prove that papaya leaf extract (Carica Papaya L.) can decrease the level of menstrual pain and prostaglandin levels in primary dysmenorrhea. Methods: A true experimental study with randomized pretest posttest control group design. There were 32 samples recruited using simple random sampling, with 16 each assigned to an experiment and control group. Numerical Rating Scale (NRS) was used to measure menstrual pain, and the level of prostaglandin was measured using the enzyme-linked immunosorbent assay (ELISA) method. Independent t-test and paired t-test were performed for data analysis. Results: There was statistically significant differencec of menstrual pain and prostaglandin level before and after intervention with p-value 0.000 (<0.005), which indiciated that papaya leaf extract had a significant effect on reducing menstrual pain. The decrease of menstrual pain in the experimental group was -3.375 and in the control group was -3.438; while the decrease of prostaglandin level in the experimental group was -56.971 and in the control group was -57.557. Conclusion: Provision of papaya leaf extract (Carica Papaya L.) significantly decreased the level of menstrual pain and prostaglandin levels in primary dysmenorrhea. Papaya leaf extract can be used as a safe and effective herbal medicine for primary dysmenorrhoea which has almost the same efficacy as mefenamic acid.
format	article
author	Siska Nurul Abidah Soeharyo Hadisaputro Runjati Syarief Thaufik Hidayat Ari Suwondo Donny Kristanto Mulyantoro
author_facet	Siska Nurul Abidah Soeharyo Hadisaputro Runjati Syarief Thaufik Hidayat Ari Suwondo Donny Kristanto Mulyantoro
author_sort	Siska Nurul Abidah
title	EFFECT OF CARICA PAPAYA L LEAF ON MENSTRUAL PAIN AND PROSTAGLANDIN LEVEL IN ADOLESCENT WITH PRIMARY DYSMENORRHEA: A TRUE EXPERIMENT
title_short	EFFECT OF CARICA PAPAYA L LEAF ON MENSTRUAL PAIN AND PROSTAGLANDIN LEVEL IN ADOLESCENT WITH PRIMARY DYSMENORRHEA: A TRUE EXPERIMENT
title_full	EFFECT OF CARICA PAPAYA L LEAF ON MENSTRUAL PAIN AND PROSTAGLANDIN LEVEL IN ADOLESCENT WITH PRIMARY DYSMENORRHEA: A TRUE EXPERIMENT
title_fullStr	EFFECT OF CARICA PAPAYA L LEAF ON MENSTRUAL PAIN AND PROSTAGLANDIN LEVEL IN ADOLESCENT WITH PRIMARY DYSMENORRHEA: A TRUE EXPERIMENT
title_full_unstemmed	EFFECT OF CARICA PAPAYA L LEAF ON MENSTRUAL PAIN AND PROSTAGLANDIN LEVEL IN ADOLESCENT WITH PRIMARY DYSMENORRHEA: A TRUE EXPERIMENT
title_sort	effect of carica papaya l leaf on menstrual pain and prostaglandin level in adolescent with primary dysmenorrhea: a true experiment
publisher	Belitung Raya Foundation
publishDate	2017
url	https://doaj.org/article/41b844fd031c404c98fd6ba14684d7b5
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_version_	1718394449442111488

EFFECT OF CARICA PAPAYA L LEAF ON MENSTRUAL PAIN AND PROSTAGLANDIN LEVEL IN ADOLESCENT WITH PRIMARY DYSMENORRHEA: A TRUE EXPERIMENT

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