D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels

Astrocytes are involved in chemoreception in brainstem areas that regulate breathing rhythm, and astrocytes are known to release d-serine. Here the authors show that astrocyte release of d-serine contributes to CO2 sensing and breathing in brainstem slices, and in vivo in awake unrestrained mice.

Guardado en:
Detalles Bibliográficos
Autores principales: S. Beltrán-Castillo, M. J. Olivares, R. A. Contreras, G. Zúñiga, I. Llona, R. von Bernhardi, J. L. Eugenín
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/41b84a8ca1b3417ea545aec89f970818
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Astrocytes are involved in chemoreception in brainstem areas that regulate breathing rhythm, and astrocytes are known to release d-serine. Here the authors show that astrocyte release of d-serine contributes to CO2 sensing and breathing in brainstem slices, and in vivo in awake unrestrained mice.