D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels
Astrocytes are involved in chemoreception in brainstem areas that regulate breathing rhythm, and astrocytes are known to release d-serine. Here the authors show that astrocyte release of d-serine contributes to CO2 sensing and breathing in brainstem slices, and in vivo in awake unrestrained mice.
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Nature Portfolio
2017
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oai:doaj.org-article:41b84a8ca1b3417ea545aec89f9708182021-12-02T14:42:45ZD-serine released by astrocytes in brainstem regulates breathing response to CO2 levels10.1038/s41467-017-00960-32041-1723https://doaj.org/article/41b84a8ca1b3417ea545aec89f9708182017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00960-3https://doaj.org/toc/2041-1723Astrocytes are involved in chemoreception in brainstem areas that regulate breathing rhythm, and astrocytes are known to release d-serine. Here the authors show that astrocyte release of d-serine contributes to CO2 sensing and breathing in brainstem slices, and in vivo in awake unrestrained mice.S. Beltrán-CastilloM. J. OlivaresR. A. ContrerasG. ZúñigaI. LlonaR. von BernhardiJ. L. EugenínNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017) |
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Science Q S. Beltrán-Castillo M. J. Olivares R. A. Contreras G. Zúñiga I. Llona R. von Bernhardi J. L. Eugenín D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels |
description |
Astrocytes are involved in chemoreception in brainstem areas that regulate breathing rhythm, and astrocytes are known to release d-serine. Here the authors show that astrocyte release of d-serine contributes to CO2 sensing and breathing in brainstem slices, and in vivo in awake unrestrained mice. |
format |
article |
author |
S. Beltrán-Castillo M. J. Olivares R. A. Contreras G. Zúñiga I. Llona R. von Bernhardi J. L. Eugenín |
author_facet |
S. Beltrán-Castillo M. J. Olivares R. A. Contreras G. Zúñiga I. Llona R. von Bernhardi J. L. Eugenín |
author_sort |
S. Beltrán-Castillo |
title |
D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels |
title_short |
D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels |
title_full |
D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels |
title_fullStr |
D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels |
title_full_unstemmed |
D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels |
title_sort |
d-serine released by astrocytes in brainstem regulates breathing response to co2 levels |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/41b84a8ca1b3417ea545aec89f970818 |
work_keys_str_mv |
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