D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels

Astrocytes are involved in chemoreception in brainstem areas that regulate breathing rhythm, and astrocytes are known to release d-serine. Here the authors show that astrocyte release of d-serine contributes to CO2 sensing and breathing in brainstem slices, and in vivo in awake unrestrained mice.

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Autores principales: S. Beltrán-Castillo, M. J. Olivares, R. A. Contreras, G. Zúñiga, I. Llona, R. von Bernhardi, J. L. Eugenín
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/41b84a8ca1b3417ea545aec89f970818
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spelling oai:doaj.org-article:41b84a8ca1b3417ea545aec89f9708182021-12-02T14:42:45ZD-serine released by astrocytes in brainstem regulates breathing response to CO2 levels10.1038/s41467-017-00960-32041-1723https://doaj.org/article/41b84a8ca1b3417ea545aec89f9708182017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00960-3https://doaj.org/toc/2041-1723Astrocytes are involved in chemoreception in brainstem areas that regulate breathing rhythm, and astrocytes are known to release d-serine. Here the authors show that astrocyte release of d-serine contributes to CO2 sensing and breathing in brainstem slices, and in vivo in awake unrestrained mice.S. Beltrán-CastilloM. J. OlivaresR. A. ContrerasG. ZúñigaI. LlonaR. von BernhardiJ. L. EugenínNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
S. Beltrán-Castillo
M. J. Olivares
R. A. Contreras
G. Zúñiga
I. Llona
R. von Bernhardi
J. L. Eugenín
D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels
description Astrocytes are involved in chemoreception in brainstem areas that regulate breathing rhythm, and astrocytes are known to release d-serine. Here the authors show that astrocyte release of d-serine contributes to CO2 sensing and breathing in brainstem slices, and in vivo in awake unrestrained mice.
format article
author S. Beltrán-Castillo
M. J. Olivares
R. A. Contreras
G. Zúñiga
I. Llona
R. von Bernhardi
J. L. Eugenín
author_facet S. Beltrán-Castillo
M. J. Olivares
R. A. Contreras
G. Zúñiga
I. Llona
R. von Bernhardi
J. L. Eugenín
author_sort S. Beltrán-Castillo
title D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels
title_short D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels
title_full D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels
title_fullStr D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels
title_full_unstemmed D-serine released by astrocytes in brainstem regulates breathing response to CO2 levels
title_sort d-serine released by astrocytes in brainstem regulates breathing response to co2 levels
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/41b84a8ca1b3417ea545aec89f970818
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AT gzuniga dserinereleasedbyastrocytesinbrainstemregulatesbreathingresponsetoco2levels
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