Association between thyroid cysts and hypertension by atherosclerosis status: a cross-sectional study

Abstract Our recent studies indicate that thyroid cysts have clinical implications. Thyroid cysts could have a positive effect on the supply of thyroid hormones. Both hyperthyroidism and hypothyroidism cause hypertension. Hypothyroidism, but not hyperthyroidism, is a risk factor for atherosclerosis....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yuji Shimizu, Shin-Ya Kawashiri, Yuko Noguchi, Yasuhiro Nagata, Takahiro Maeda, Naomi Hayashida
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/41b98daabff740a08ddc87ee361db97c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:41b98daabff740a08ddc87ee361db97c
record_format	dspace
spelling	oai:doaj.org-article:41b98daabff740a08ddc87ee361db97c2021-12-02T16:24:50ZAssociation between thyroid cysts and hypertension by atherosclerosis status: a cross-sectional study10.1038/s41598-021-92970-x2045-2322https://doaj.org/article/41b98daabff740a08ddc87ee361db97c2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92970-xhttps://doaj.org/toc/2045-2322Abstract Our recent studies indicate that thyroid cysts have clinical implications. Thyroid cysts could have a positive effect on the supply of thyroid hormones. Both hyperthyroidism and hypothyroidism cause hypertension. Hypothyroidism, but not hyperthyroidism, is a risk factor for atherosclerosis. Therefore, thyroid cysts could be associated with hypertension, and atherosclerosis might influence the association between thyroid cysts and hypertension. To evaluate the clinical significance of thyroid cysts, a cross-sectional study was conducted with 1801 Japanese aged 40–74 years. Thyroid cysts were significantly positively associated with hypertension in participants without atherosclerosis. However, there was a significant inverse association in those with atherosclerosis. The potential confounding factor adjusted odd ratios and 95% confidence intervals (95% CIs) were 1.49 (95% CI 1.17–1.90) for participants without atherosclerosis and 0.49 (95% CI 0.24–0.98) for those with atherosclerosis. The present study demonstrates that thyroid cysts have clinical implications because thyroid cysts support thyroid hormone activity. Our findings provide sufficient evidence to develop a risk assessment for hypertension for the general population, even though further research is required.Yuji ShimizuShin-Ya KawashiriYuko NoguchiYasuhiro NagataTakahiro MaedaNaomi HayashidaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yuji Shimizu Shin-Ya Kawashiri Yuko Noguchi Yasuhiro Nagata Takahiro Maeda Naomi Hayashida Association between thyroid cysts and hypertension by atherosclerosis status: a cross-sectional study
description	Abstract Our recent studies indicate that thyroid cysts have clinical implications. Thyroid cysts could have a positive effect on the supply of thyroid hormones. Both hyperthyroidism and hypothyroidism cause hypertension. Hypothyroidism, but not hyperthyroidism, is a risk factor for atherosclerosis. Therefore, thyroid cysts could be associated with hypertension, and atherosclerosis might influence the association between thyroid cysts and hypertension. To evaluate the clinical significance of thyroid cysts, a cross-sectional study was conducted with 1801 Japanese aged 40–74 years. Thyroid cysts were significantly positively associated with hypertension in participants without atherosclerosis. However, there was a significant inverse association in those with atherosclerosis. The potential confounding factor adjusted odd ratios and 95% confidence intervals (95% CIs) were 1.49 (95% CI 1.17–1.90) for participants without atherosclerosis and 0.49 (95% CI 0.24–0.98) for those with atherosclerosis. The present study demonstrates that thyroid cysts have clinical implications because thyroid cysts support thyroid hormone activity. Our findings provide sufficient evidence to develop a risk assessment for hypertension for the general population, even though further research is required.
format	article
author	Yuji Shimizu Shin-Ya Kawashiri Yuko Noguchi Yasuhiro Nagata Takahiro Maeda Naomi Hayashida
author_facet	Yuji Shimizu Shin-Ya Kawashiri Yuko Noguchi Yasuhiro Nagata Takahiro Maeda Naomi Hayashida
author_sort	Yuji Shimizu
title	Association between thyroid cysts and hypertension by atherosclerosis status: a cross-sectional study
title_short	Association between thyroid cysts and hypertension by atherosclerosis status: a cross-sectional study
title_full	Association between thyroid cysts and hypertension by atherosclerosis status: a cross-sectional study
title_fullStr	Association between thyroid cysts and hypertension by atherosclerosis status: a cross-sectional study
title_full_unstemmed	Association between thyroid cysts and hypertension by atherosclerosis status: a cross-sectional study
title_sort	association between thyroid cysts and hypertension by atherosclerosis status: a cross-sectional study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/41b98daabff740a08ddc87ee361db97c
work_keys_str_mv	AT yujishimizu associationbetweenthyroidcystsandhypertensionbyatherosclerosisstatusacrosssectionalstudy AT shinyakawashiri associationbetweenthyroidcystsandhypertensionbyatherosclerosisstatusacrosssectionalstudy AT yukonoguchi associationbetweenthyroidcystsandhypertensionbyatherosclerosisstatusacrosssectionalstudy AT yasuhironagata associationbetweenthyroidcystsandhypertensionbyatherosclerosisstatusacrosssectionalstudy AT takahiromaeda associationbetweenthyroidcystsandhypertensionbyatherosclerosisstatusacrosssectionalstudy AT naomihayashida associationbetweenthyroidcystsandhypertensionbyatherosclerosisstatusacrosssectionalstudy
_version_	1718384105817636864

Association between thyroid cysts and hypertension by atherosclerosis status: a cross-sectional study

Ejemplares similares