Complete Genome Analysis of Undecylprodigiosin Pigment Biosynthesizing Marine Streptomyces Species Displaying Potential Bioactive Applications

Marine Streptomyces species are underexplored for their pigment molecules and genes. In this study, we report the genome of the undecylprodigiosin biosynthesizing gene cluster carrying Streptomyces sp. strain BSE6.1, displaying antioxidant, antimicrobial, and st...

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Autores principales:	Chatragadda Ramesh, Maile Anwesh, Nambali Valsalan Vinithkumar, Ramalingam Kirubagaran, Laurent Dufossé
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	prodigiosin undecylprodigiosin marine sediment antioxidant antimicrobial type III PKS genes Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/41d743310f834f3d8de63a90244638c6
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id	oai:doaj.org-article:41d743310f834f3d8de63a90244638c6
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spelling	oai:doaj.org-article:41d743310f834f3d8de63a90244638c62021-11-25T18:24:36ZComplete Genome Analysis of Undecylprodigiosin Pigment Biosynthesizing Marine <i>Streptomyces</i> Species Displaying Potential Bioactive Applications10.3390/microorganisms91122492076-2607https://doaj.org/article/41d743310f834f3d8de63a90244638c62021-10-01T00:00:00Zhttps://www.mdpi.com/2076-2607/9/11/2249https://doaj.org/toc/2076-2607Marine <i>Streptomyces</i> species are underexplored for their pigment molecules and genes. In this study, we report the genome of the undecylprodigiosin biosynthesizing gene cluster carrying <i>Streptomyces</i> sp. strain BSE6.1, displaying antioxidant, antimicrobial, and staining properties. This Gram-positive obligate aerobic bacterium was isolated from the coastal sediment of the Andaman and Nicobar Islands, India. Pink to reddish pigmented colonies with whitish powdery spores on both agar and broth media are the important morphological characteristics of this bacterium. Growth tolerance to NaCl concentrations was 2 to 7%. The assembled genome of <i>Streptomyces</i> sp. BSE6.1 contains one linear chromosome 8.02 Mb in length with 7157 protein-coding genes, 82 tRNAs, 3 rRNAs and at least 11 gene clusters related to the synthesis of various secondary metabolites, including undecylprodigiosin. This strain carries type I, type II, and type III polyketide synthases (PKS) genes. Type I PKS gene cluster is involved in the biosynthesis of red pigment undecylprodigiosin of BSE6.1, similar to the one found in the <i>S. coelicolor</i> A3(2). This red pigment was reported to have various applications in the food and pharmaceutical industries. The genome of <i>Streptomyces</i> sp. BSE6.1 was submitted to NCBI with a BioProject ID of PRJNA514840 (Sequence Read Archive ID: SRR10849367 and Genome accession ID: CP085300).Chatragadda RameshMaile AnweshNambali Valsalan VinithkumarRamalingam KirubagaranLaurent DufosséMDPI AGarticleprodigiosinundecylprodigiosinmarine sedimentantioxidantantimicrobialtype III PKS genesBiology (General)QH301-705.5ENMicroorganisms, Vol 9, Iss 2249, p 2249 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	prodigiosin undecylprodigiosin marine sediment antioxidant antimicrobial type III PKS genes Biology (General) QH301-705.5
spellingShingle	prodigiosin undecylprodigiosin marine sediment antioxidant antimicrobial type III PKS genes Biology (General) QH301-705.5 Chatragadda Ramesh Maile Anwesh Nambali Valsalan Vinithkumar Ramalingam Kirubagaran Laurent Dufossé Complete Genome Analysis of Undecylprodigiosin Pigment Biosynthesizing Marine <i>Streptomyces</i> Species Displaying Potential Bioactive Applications
description	Marine <i>Streptomyces</i> species are underexplored for their pigment molecules and genes. In this study, we report the genome of the undecylprodigiosin biosynthesizing gene cluster carrying <i>Streptomyces</i> sp. strain BSE6.1, displaying antioxidant, antimicrobial, and staining properties. This Gram-positive obligate aerobic bacterium was isolated from the coastal sediment of the Andaman and Nicobar Islands, India. Pink to reddish pigmented colonies with whitish powdery spores on both agar and broth media are the important morphological characteristics of this bacterium. Growth tolerance to NaCl concentrations was 2 to 7%. The assembled genome of <i>Streptomyces</i> sp. BSE6.1 contains one linear chromosome 8.02 Mb in length with 7157 protein-coding genes, 82 tRNAs, 3 rRNAs and at least 11 gene clusters related to the synthesis of various secondary metabolites, including undecylprodigiosin. This strain carries type I, type II, and type III polyketide synthases (PKS) genes. Type I PKS gene cluster is involved in the biosynthesis of red pigment undecylprodigiosin of BSE6.1, similar to the one found in the <i>S. coelicolor</i> A3(2). This red pigment was reported to have various applications in the food and pharmaceutical industries. The genome of <i>Streptomyces</i> sp. BSE6.1 was submitted to NCBI with a BioProject ID of PRJNA514840 (Sequence Read Archive ID: SRR10849367 and Genome accession ID: CP085300).
format	article
author	Chatragadda Ramesh Maile Anwesh Nambali Valsalan Vinithkumar Ramalingam Kirubagaran Laurent Dufossé
author_facet	Chatragadda Ramesh Maile Anwesh Nambali Valsalan Vinithkumar Ramalingam Kirubagaran Laurent Dufossé
author_sort	Chatragadda Ramesh
title	Complete Genome Analysis of Undecylprodigiosin Pigment Biosynthesizing Marine <i>Streptomyces</i> Species Displaying Potential Bioactive Applications
title_short	Complete Genome Analysis of Undecylprodigiosin Pigment Biosynthesizing Marine <i>Streptomyces</i> Species Displaying Potential Bioactive Applications
title_full	Complete Genome Analysis of Undecylprodigiosin Pigment Biosynthesizing Marine <i>Streptomyces</i> Species Displaying Potential Bioactive Applications
title_fullStr	Complete Genome Analysis of Undecylprodigiosin Pigment Biosynthesizing Marine <i>Streptomyces</i> Species Displaying Potential Bioactive Applications
title_full_unstemmed	Complete Genome Analysis of Undecylprodigiosin Pigment Biosynthesizing Marine <i>Streptomyces</i> Species Displaying Potential Bioactive Applications
title_sort	complete genome analysis of undecylprodigiosin pigment biosynthesizing marine <i>streptomyces</i> species displaying potential bioactive applications
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/41d743310f834f3d8de63a90244638c6
work_keys_str_mv	AT chatragaddaramesh completegenomeanalysisofundecylprodigiosinpigmentbiosynthesizingmarineistreptomycesispeciesdisplayingpotentialbioactiveapplications AT maileanwesh completegenomeanalysisofundecylprodigiosinpigmentbiosynthesizingmarineistreptomycesispeciesdisplayingpotentialbioactiveapplications AT nambalivalsalanvinithkumar completegenomeanalysisofundecylprodigiosinpigmentbiosynthesizingmarineistreptomycesispeciesdisplayingpotentialbioactiveapplications AT ramalingamkirubagaran completegenomeanalysisofundecylprodigiosinpigmentbiosynthesizingmarineistreptomycesispeciesdisplayingpotentialbioactiveapplications AT laurentdufosse completegenomeanalysisofundecylprodigiosinpigmentbiosynthesizingmarineistreptomycesispeciesdisplayingpotentialbioactiveapplications
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Complete Genome Analysis of Undecylprodigiosin Pigment Biosynthesizing Marine <i>Streptomyces</i> Species Displaying Potential Bioactive Applications

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