Effects of infection history on dengue virus infection and pathogenicity

Lack of knowledge of individual infection history hinders understanding of immunological interactions among DENV serotypes. Here, the authors introduce a framework to infer the relationship between unobserved infection history and subsequent infection and disease risk, and find complex dependencies.

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Autores principales: Tim K. Tsang, Samson L. Ghebremariam, Lionel Gresh, Aubree Gordon, M. Elizabeth Halloran, Leah C. Katzelnick, Diana Patricia Rojas, Guillermina Kuan, Angel Balmaseda, Jonathan Sugimoto, Eva Harris, Ira M. Longini, Yang Yang
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/41de2292faac4ea497c6bcb645c19f5d
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spelling oai:doaj.org-article:41de2292faac4ea497c6bcb645c19f5d2021-12-02T14:35:43ZEffects of infection history on dengue virus infection and pathogenicity10.1038/s41467-019-09193-y2041-1723https://doaj.org/article/41de2292faac4ea497c6bcb645c19f5d2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09193-yhttps://doaj.org/toc/2041-1723Lack of knowledge of individual infection history hinders understanding of immunological interactions among DENV serotypes. Here, the authors introduce a framework to infer the relationship between unobserved infection history and subsequent infection and disease risk, and find complex dependencies.Tim K. TsangSamson L. GhebremariamLionel GreshAubree GordonM. Elizabeth HalloranLeah C. KatzelnickDiana Patricia RojasGuillermina KuanAngel BalmasedaJonathan SugimotoEva HarrisIra M. LonginiYang YangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tim K. Tsang
Samson L. Ghebremariam
Lionel Gresh
Aubree Gordon
M. Elizabeth Halloran
Leah C. Katzelnick
Diana Patricia Rojas
Guillermina Kuan
Angel Balmaseda
Jonathan Sugimoto
Eva Harris
Ira M. Longini
Yang Yang
Effects of infection history on dengue virus infection and pathogenicity
description Lack of knowledge of individual infection history hinders understanding of immunological interactions among DENV serotypes. Here, the authors introduce a framework to infer the relationship between unobserved infection history and subsequent infection and disease risk, and find complex dependencies.
format article
author Tim K. Tsang
Samson L. Ghebremariam
Lionel Gresh
Aubree Gordon
M. Elizabeth Halloran
Leah C. Katzelnick
Diana Patricia Rojas
Guillermina Kuan
Angel Balmaseda
Jonathan Sugimoto
Eva Harris
Ira M. Longini
Yang Yang
author_facet Tim K. Tsang
Samson L. Ghebremariam
Lionel Gresh
Aubree Gordon
M. Elizabeth Halloran
Leah C. Katzelnick
Diana Patricia Rojas
Guillermina Kuan
Angel Balmaseda
Jonathan Sugimoto
Eva Harris
Ira M. Longini
Yang Yang
author_sort Tim K. Tsang
title Effects of infection history on dengue virus infection and pathogenicity
title_short Effects of infection history on dengue virus infection and pathogenicity
title_full Effects of infection history on dengue virus infection and pathogenicity
title_fullStr Effects of infection history on dengue virus infection and pathogenicity
title_full_unstemmed Effects of infection history on dengue virus infection and pathogenicity
title_sort effects of infection history on dengue virus infection and pathogenicity
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/41de2292faac4ea497c6bcb645c19f5d
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