Renin-angiotensin system inhibitor attenuates oxidative stress induced human coronary artery endothelial cell dysfunction via the PI3K/AKT/mTOR pathway

Introduction The renin-angiotensin system is associated with blood pressure regulation, inflammation, oxidative stress and insulin resistance. It can decrease intracellular oxidative stress. Stimulation with H 2 O 2 leads to increased oxidative stress and activation of the AKT/mTOR pathway. However...

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Bibliographic Details
Main Authors: Xuekun Shi, Yuhua Guan, Shaoyan Jiang, Tiandong Li, Bing Sun, Huan Cheng
Format: article
Language:EN
Published: Termedia Publishing House 2018
Subjects:
R
Online Access:https://doaj.org/article/41de30315c8f433fa7c4c5fcc3ec009c
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