Spatiotemporal dynamics of lesion-induced axonal sprouting and its relation to functional architecture of the cerebellum
Neurodegenerative lesions induce sprouting from surviving axons, but the patterns of re-innervation of these collaterals in relation to existing functional networks remains unclear. Here the authors performed long term in vivoimaging in mice, of sprouts from cerebellar climbing fibers after a lesion...
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| Autores principales: | , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/41e4009724e94b1894d6ea1d6604f795 |
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| Sumario: | Neurodegenerative lesions induce sprouting from surviving axons, but the patterns of re-innervation of these collaterals in relation to existing functional networks remains unclear. Here the authors performed long term in vivoimaging in mice, of sprouts from cerebellar climbing fibers after a lesion, and describe the patterns of connectivity relative to functionally active zones. |
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