EVALUATION OF HISTOLOGICAL PARAMETERS IN PATIENTS WITH CLINICAL REMISSION OF ULCERATIVE COLITIS

Goal of the study: to examine histological changes in the mucosa of patients with clinical remission of ulcerative colitis and compare these changes with endoscopic parameters. Methods: 25 patients with clinical remission of ulcerative colitis underwent fibrocolonoscopy with biopsy and histological...

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Autores principales:	O. B. Shchukina, E. A. Kondrashina, A. M. Kharitidis, A. V. Botina, E. A. Markova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2014
Materias:	ulcerative colitis mucosal healing eosinophils increased density of infiltrate Science Q
Acceso en línea:	https://doaj.org/article/41eb4e9150544590a90349f6ea6bf8ff
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spelling	oai:doaj.org-article:41eb4e9150544590a90349f6ea6bf8ff2021-11-23T06:14:31ZEVALUATION OF HISTOLOGICAL PARAMETERS IN PATIENTS WITH CLINICAL REMISSION OF ULCERATIVE COLITIS2541-94202587-9596https://doaj.org/article/41eb4e9150544590a90349f6ea6bf8ff2014-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1832https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Goal of the study: to examine histological changes in the mucosa of patients with clinical remission of ulcerative colitis and compare these changes with endoscopic parameters. Methods: 25 patients with clinical remission of ulcerative colitis underwent fibrocolonoscopy with biopsy and histological assessment of disease activity on the Gebos scale. Due to limited number of observations, it was possible to identify comparable study and control groups only for two parameters: increased eosinophil count and increased density of infiltrate in the mucosa. Results of the study: erosions, cryptitis, hyperplasia of lymphoid structures and infiltration of the intestinal mucosa with neutrophilic leukocyte often observed in the presence of increased eosinophil count in the mucosa and/or increased density of the cellular infiltrate. Conclusion: increased eosinophil count and/or increased density of the cellular infiltrate in the mucosa often accompanied by other signs of lack of the mucosa healing. Confirmation of complete remission of the disease requires histological control for exclusion of the inflammation signs.O. B. ShchukinaE. A. KondrashinaA. M. KharitidisA. V. BotinaE. A. MarkovaScientific Сentre for Family Health and Human Reproduction Problemsarticleulcerative colitismucosal healingeosinophilsincreased density of infiltrateScienceQRUActa Biomedica Scientifica, Vol 0, Iss 6, Pp 39-43 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	ulcerative colitis mucosal healing eosinophils increased density of infiltrate Science Q
spellingShingle	ulcerative colitis mucosal healing eosinophils increased density of infiltrate Science Q O. B. Shchukina E. A. Kondrashina A. M. Kharitidis A. V. Botina E. A. Markova EVALUATION OF HISTOLOGICAL PARAMETERS IN PATIENTS WITH CLINICAL REMISSION OF ULCERATIVE COLITIS
description	Goal of the study: to examine histological changes in the mucosa of patients with clinical remission of ulcerative colitis and compare these changes with endoscopic parameters. Methods: 25 patients with clinical remission of ulcerative colitis underwent fibrocolonoscopy with biopsy and histological assessment of disease activity on the Gebos scale. Due to limited number of observations, it was possible to identify comparable study and control groups only for two parameters: increased eosinophil count and increased density of infiltrate in the mucosa. Results of the study: erosions, cryptitis, hyperplasia of lymphoid structures and infiltration of the intestinal mucosa with neutrophilic leukocyte often observed in the presence of increased eosinophil count in the mucosa and/or increased density of the cellular infiltrate. Conclusion: increased eosinophil count and/or increased density of the cellular infiltrate in the mucosa often accompanied by other signs of lack of the mucosa healing. Confirmation of complete remission of the disease requires histological control for exclusion of the inflammation signs.
format	article
author	O. B. Shchukina E. A. Kondrashina A. M. Kharitidis A. V. Botina E. A. Markova
author_facet	O. B. Shchukina E. A. Kondrashina A. M. Kharitidis A. V. Botina E. A. Markova
author_sort	O. B. Shchukina
title	EVALUATION OF HISTOLOGICAL PARAMETERS IN PATIENTS WITH CLINICAL REMISSION OF ULCERATIVE COLITIS
title_short	EVALUATION OF HISTOLOGICAL PARAMETERS IN PATIENTS WITH CLINICAL REMISSION OF ULCERATIVE COLITIS
title_full	EVALUATION OF HISTOLOGICAL PARAMETERS IN PATIENTS WITH CLINICAL REMISSION OF ULCERATIVE COLITIS
title_fullStr	EVALUATION OF HISTOLOGICAL PARAMETERS IN PATIENTS WITH CLINICAL REMISSION OF ULCERATIVE COLITIS
title_full_unstemmed	EVALUATION OF HISTOLOGICAL PARAMETERS IN PATIENTS WITH CLINICAL REMISSION OF ULCERATIVE COLITIS
title_sort	evaluation of histological parameters in patients with clinical remission of ulcerative colitis
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2014
url	https://doaj.org/article/41eb4e9150544590a90349f6ea6bf8ff
work_keys_str_mv	AT obshchukina evaluationofhistologicalparametersinpatientswithclinicalremissionofulcerativecolitis AT eakondrashina evaluationofhistologicalparametersinpatientswithclinicalremissionofulcerativecolitis AT amkharitidis evaluationofhistologicalparametersinpatientswithclinicalremissionofulcerativecolitis AT avbotina evaluationofhistologicalparametersinpatientswithclinicalremissionofulcerativecolitis AT eamarkova evaluationofhistologicalparametersinpatientswithclinicalremissionofulcerativecolitis
_version_	1718417065993306112

EVALUATION OF HISTOLOGICAL PARAMETERS IN PATIENTS WITH CLINICAL REMISSION OF ULCERATIVE COLITIS

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