Neuromedin U signaling regulates retrieval of learned salt avoidance in a C. elegans gustatory circuit

Neuromedin U signaling regulates retrieval of learned salt avoidance in a C. elegans gustatory circuit

Learning and memory are regulated by neuropeptides. Here, the authors show that the neuropeptide CAPA-1 and its receptor NMUR-1 are required to retrieve learned salt avoidance in C. elegans. CAPA-1/NMUR-1 activation in AFD sensory neurons modulates locomotor programs to express learned avoidance.

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Bibliographic Details
Main Authors: Jan Watteyne, Katleen Peymen, Petrus Van der Auwera, Charline Borghgraef, Elke Vandewyer, Sara Van Damme, Iene Rutten, Jeroen Lammertyn, Rob Jelier, Liliane Schoofs, Isabel Beets
Format: article
Language:EN
Published: Nature Portfolio 2020
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Science
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Online Access:https://doaj.org/article/41ef0f998f65410bada8ea220c20a4f1
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Summary:Learning and memory are regulated by neuropeptides. Here, the authors show that the neuropeptide CAPA-1 and its receptor NMUR-1 are required to retrieve learned salt avoidance in C. elegans. CAPA-1/NMUR-1 activation in AFD sensory neurons modulates locomotor programs to express learned avoidance.

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