Stroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin K antagonist oral anticoagulants

Mohit K Turagam, Poonam Velagapudi, Greg C FlakerDivision of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO, USAAbstract: Stroke prevention in elderly atrial fibrillation patients remains a challenge. There is a high risk of stroke and systemic thromboembolism but a...

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Autores principales:	Turagam MK, Velagapudi P, Flaker GC
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Non-vitamin K antagonist oral anticoagulants novel oral anticoagulants warfarin dabigatran rivaroxaban apixaban edoxaban Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/41f59bd399bb44898f5c2dfc00feaa36
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spelling	oai:doaj.org-article:41f59bd399bb44898f5c2dfc00feaa362021-12-02T07:54:37ZStroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin K antagonist oral anticoagulants1178-1998https://doaj.org/article/41f59bd399bb44898f5c2dfc00feaa362015-09-01T00:00:00Zhttps://www.dovepress.com/stroke-prevention-in-the-elderly-atrial-fibrillation-patient-with-como-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Mohit K Turagam, Poonam Velagapudi, Greg C FlakerDivision of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO, USAAbstract: Stroke prevention in elderly atrial fibrillation patients remains a challenge. There is a high risk of stroke and systemic thromboembolism but also a high risk of bleeding if anticoagulants are prescribed. The elderly have increased chronic kidney disease, coronary artery disease, polypharmacy, and overall frailty. For all these reasons, anticoagulant use is underutilized in the elderly. In this manuscript, the benefits of non-vitamin K antagonist oral anticoagulants compared with warfarin in the elderly patient population with multiple comorbid conditions are reviewed.Keywords: non-vitamin K antagonist oral anticoagulants, novel oral anticoagulants, warfarin, dabigatran, rivaroxaban, apixaban, edoxabanTuragam MKVelagapudi PFlaker GCDove Medical PressarticleNon-vitamin K antagonist oral anticoagulantsnovel oral anticoagulantswarfarindabigatranrivaroxabanapixabanedoxabanGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 10, Pp 1431-1444 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Non-vitamin K antagonist oral anticoagulants novel oral anticoagulants warfarin dabigatran rivaroxaban apixaban edoxaban Geriatrics RC952-954.6
spellingShingle	Non-vitamin K antagonist oral anticoagulants novel oral anticoagulants warfarin dabigatran rivaroxaban apixaban edoxaban Geriatrics RC952-954.6 Turagam MK Velagapudi P Flaker GC Stroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin K antagonist oral anticoagulants
description	Mohit K Turagam, Poonam Velagapudi, Greg C FlakerDivision of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO, USAAbstract: Stroke prevention in elderly atrial fibrillation patients remains a challenge. There is a high risk of stroke and systemic thromboembolism but also a high risk of bleeding if anticoagulants are prescribed. The elderly have increased chronic kidney disease, coronary artery disease, polypharmacy, and overall frailty. For all these reasons, anticoagulant use is underutilized in the elderly. In this manuscript, the benefits of non-vitamin K antagonist oral anticoagulants compared with warfarin in the elderly patient population with multiple comorbid conditions are reviewed.Keywords: non-vitamin K antagonist oral anticoagulants, novel oral anticoagulants, warfarin, dabigatran, rivaroxaban, apixaban, edoxaban
format	article
author	Turagam MK Velagapudi P Flaker GC
author_facet	Turagam MK Velagapudi P Flaker GC
author_sort	Turagam MK
title	Stroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin K antagonist oral anticoagulants
title_short	Stroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin K antagonist oral anticoagulants
title_full	Stroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin K antagonist oral anticoagulants
title_fullStr	Stroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin K antagonist oral anticoagulants
title_full_unstemmed	Stroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin K antagonist oral anticoagulants
title_sort	stroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin k antagonist oral anticoagulants
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/41f59bd399bb44898f5c2dfc00feaa36
work_keys_str_mv	AT turagammk strokepreventionintheelderlyatrialfibrillationpatientwithcomorbidconditionsfocusonnonvitaminkantagonistoralanticoagulants AT velagapudip strokepreventionintheelderlyatrialfibrillationpatientwithcomorbidconditionsfocusonnonvitaminkantagonistoralanticoagulants AT flakergc strokepreventionintheelderlyatrialfibrillationpatientwithcomorbidconditionsfocusonnonvitaminkantagonistoralanticoagulants
_version_	1718399098015449088

Stroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin K antagonist oral anticoagulants

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