Shotgun-based proteomics of extracellular vesicles in Alzheimer’s disease reveals biomarkers involved in immunological and coagulation pathways

Abstract Alzheimer’s disease (AD) is the most common form of dementia and without readily available clinical biomarkers. Blood-derived proteins are routinely used for diagnostics; however, comprehensive plasma profiling is challenging due to the dynamic range in protein concentrations. Extracellular...

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Bibliographic Details
Main Authors: Jonas Ellegaard Nielsen, Bent Honoré, Karsten Vestergård, Raluca Georgiana Maltesen, Gunna Christiansen, Anna Uhd Bøge, Søren Risom Kristensen, Shona Pedersen
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/41fc1d200018460e9fa27e434581d2aa
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