A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis

Photodynamic therapy is usually ineffective against deeply seated metastatic tumors due to poor penetration of the excitation light. Here, the authors design a biomimetic nanoreactor which can convert nutriment glucose into toxic singlet oxygen via chemiluminescence resonance energy transfer with no...

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Autores principales:	Zhengze Yu, Ping Zhou, Wei Pan, Na Li, Bo Tang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/42045ab49bbe490b86ea2faef490e338
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spelling	oai:doaj.org-article:42045ab49bbe490b86ea2faef490e3382021-12-02T16:49:22ZA biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis10.1038/s41467-018-07197-82041-1723https://doaj.org/article/42045ab49bbe490b86ea2faef490e3382018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07197-8https://doaj.org/toc/2041-1723Photodynamic therapy is usually ineffective against deeply seated metastatic tumors due to poor penetration of the excitation light. Here, the authors design a biomimetic nanoreactor which can convert nutriment glucose into toxic singlet oxygen via chemiluminescence resonance energy transfer with no light excitation and demonstrate its high efficacy in a mouse lung metastatic model.Zhengze YuPing ZhouWei PanNa LiBo TangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhengze Yu Ping Zhou Wei Pan Na Li Bo Tang A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis
description	Photodynamic therapy is usually ineffective against deeply seated metastatic tumors due to poor penetration of the excitation light. Here, the authors design a biomimetic nanoreactor which can convert nutriment glucose into toxic singlet oxygen via chemiluminescence resonance energy transfer with no light excitation and demonstrate its high efficacy in a mouse lung metastatic model.
format	article
author	Zhengze Yu Ping Zhou Wei Pan Na Li Bo Tang
author_facet	Zhengze Yu Ping Zhou Wei Pan Na Li Bo Tang
author_sort	Zhengze Yu
title	A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis
title_short	A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis
title_full	A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis
title_fullStr	A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis
title_full_unstemmed	A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis
title_sort	biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/42045ab49bbe490b86ea2faef490e338
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A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis

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