Increased NRG1-ErbB4 signaling in human symptomatic epilepsy

Abstract Previous studies have shown that the neuregulin 1 (NRG1)-ErbB4 signaling pathway may regulate the excitability of fast-spiking neurons in the frontal cortex and participate in primary epilepsy pathogenesis. However, the exact roles and mechanism for NRG1/ErbB4 in human symptomatic epilepsy...

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Auteurs principaux: Jun-Ming Zhu, Ke-Xin Li, Shu-Xia Cao, Xiao-Juan Chen, Chen-Jie Shen, Ying Zhang, Hong-Yan Geng, Bi-Qing Chen, Hong Lian, Jian-Min Zhang, Xiao-Ming Li
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/420724930bfd4bf49c99a6881c10b50e
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