BART inhibits pancreatic cancer cell invasion by PKCα inactivation through binding to ANX7.
A novel function for the binder of Arl two (BART) molecule in pancreatic cancer cells is reported. BART inhibits invasiveness of pancreatic cancer cells through binding to a Ca(2+)-dependent, phosphorylated, guanosine triphosphatase (GTPase) membrane fusion protein, annexin7 (ANX7). A tumor suppress...
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Autores principales: | Keisuke Taniuchi, Kunihiko Yokotani, Toshiji Saibara |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/420a29af32d44633811de783f5d3c27b |
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