Predictors of weight loss and maintenance in patients treated with antiobesity drugs

Federica Guaraldi1, Uberto Pagotto2, Renato Pasquali21Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; 2Division of Endocrinology, Department of Clinical Medicine, S Orsola-Malpighi Hospital, Alma Mater Studiorum University, Bologna, ItalyBackground: The...

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Autores principales:	Guaraldi F, Pagotto U, Pasquali R
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/4213a4d25f75424e92a0a9730527768c
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spelling	oai:doaj.org-article:4213a4d25f75424e92a0a9730527768c2021-12-02T04:46:13ZPredictors of weight loss and maintenance in patients treated with antiobesity drugs1178-7007https://doaj.org/article/4213a4d25f75424e92a0a9730527768c2011-06-01T00:00:00Zhttp://www.dovepress.com/predictors-of-weight-loss-and-maintenance-in-patients-treated-with-ant-a7684https://doaj.org/toc/1178-7007Federica Guaraldi1, Uberto Pagotto2, Renato Pasquali21Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; 2Division of Endocrinology, Department of Clinical Medicine, S Orsola-Malpighi Hospital, Alma Mater Studiorum University, Bologna, ItalyBackground: The prevalence of obesity and related diseases has increased enormously in the last few decades, becoming a very important medical and social issue. Because of the increasing number of people who need weight loss therapies and the high costs associated with these, the search for reliable predictors of success for weight loss and weight maintenance treatments has become a priority.Objective: A literature review was undertaken to identify possible predictors of outcome of weight loss and weight maintenance in patients treated with antiobesity drugs.Results: For the majority of variables, published data are not sufficient to define their role on final outcomes. Among all considered factors, only early response to treatment appeared to be a reliable positive predictor, and diabetes a negative predictor of weight loss and maintenance.Conclusion: To date, no definitive results have been obtained. Due to the great benefits of reliable predictors of outcome associated to currently available antiobesity drugs and those under development, identifying these predictors has to be supported and encouraged.Keywords: obesity, weight loss predictors, pharmacological treatmentGuaraldi FPagotto UPasquali RDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2011, Iss default, Pp 229-243 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Guaraldi F Pagotto U Pasquali R Predictors of weight loss and maintenance in patients treated with antiobesity drugs
description	Federica Guaraldi1, Uberto Pagotto2, Renato Pasquali21Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; 2Division of Endocrinology, Department of Clinical Medicine, S Orsola-Malpighi Hospital, Alma Mater Studiorum University, Bologna, ItalyBackground: The prevalence of obesity and related diseases has increased enormously in the last few decades, becoming a very important medical and social issue. Because of the increasing number of people who need weight loss therapies and the high costs associated with these, the search for reliable predictors of success for weight loss and weight maintenance treatments has become a priority.Objective: A literature review was undertaken to identify possible predictors of outcome of weight loss and weight maintenance in patients treated with antiobesity drugs.Results: For the majority of variables, published data are not sufficient to define their role on final outcomes. Among all considered factors, only early response to treatment appeared to be a reliable positive predictor, and diabetes a negative predictor of weight loss and maintenance.Conclusion: To date, no definitive results have been obtained. Due to the great benefits of reliable predictors of outcome associated to currently available antiobesity drugs and those under development, identifying these predictors has to be supported and encouraged.Keywords: obesity, weight loss predictors, pharmacological treatment
format	article
author	Guaraldi F Pagotto U Pasquali R
author_facet	Guaraldi F Pagotto U Pasquali R
author_sort	Guaraldi F
title	Predictors of weight loss and maintenance in patients treated with antiobesity drugs
title_short	Predictors of weight loss and maintenance in patients treated with antiobesity drugs
title_full	Predictors of weight loss and maintenance in patients treated with antiobesity drugs
title_fullStr	Predictors of weight loss and maintenance in patients treated with antiobesity drugs
title_full_unstemmed	Predictors of weight loss and maintenance in patients treated with antiobesity drugs
title_sort	predictors of weight loss and maintenance in patients treated with antiobesity drugs
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/4213a4d25f75424e92a0a9730527768c
work_keys_str_mv	AT guaraldif predictorsofweightlossandmaintenanceinpatientstreatedwithantiobesitydrugs AT pagottou predictorsofweightlossandmaintenanceinpatientstreatedwithantiobesitydrugs AT pasqualir predictorsofweightlossandmaintenanceinpatientstreatedwithantiobesitydrugs
_version_	1718401055203524608

Predictors of weight loss and maintenance in patients treated with antiobesity drugs

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