Assessment of growth factors with three different platelet preparations, namely platelet-rich fibrin, platelet-rich plasma, and lyophilized platelet: An In vitro study

Assessment of growth factors with three different platelet preparations namely platelet rich fibrin, platelet rich plasma and lyophilized platelet-An invitro study Abstract Enhancing wound healing with patients own blood, particularly the platelet preparations have gained more popularity recently. T...

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Autores principales:	R Hariprasad, T L Suganya, Serin Sarah John, P Rajesh Raj, Feby kuriakose, V N Anoop
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	elisa growth factors lyophilized platelet platelet preparations surgical additives Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142
Acceso en línea:	https://doaj.org/article/42180ab1c18b44d5a08e82c5c0c62b52
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spelling	oai:doaj.org-article:42180ab1c18b44d5a08e82c5c0c62b522021-11-19T12:15:53ZAssessment of growth factors with three different platelet preparations, namely platelet-rich fibrin, platelet-rich plasma, and lyophilized platelet: An In vitro study0975-740610.4103/jpbs.jpbs_358_21https://doaj.org/article/42180ab1c18b44d5a08e82c5c0c62b522021-01-01T00:00:00Zhttp://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=6;spage=1696;epage=1699;aulast=Hariprasadhttps://doaj.org/toc/0975-7406Assessment of growth factors with three different platelet preparations namely platelet rich fibrin, platelet rich plasma and lyophilized platelet-An invitro study Abstract Enhancing wound healing with patients own blood, particularly the platelet preparations have gained more popularity recently. These platelets excrete large amount of growth factors and cytokines that are associated with the healing process and regeneration. Even though these platelet concentrates are widely used in various forms, the mechanism behind that remains unclear. Therefore, this study aims at investigating the levels of growth factors in three different platelet preparations namely platelet rich plasma (PRP), platelet rich fibrin (PRF) and lyophilized platelets. Materials and Methods Autologous blood for preparing the platelet preparations was obtained from healthy donors aged between 25 to 35 years. The samples were then divided into three experimental groups. The preparation of PRP was done with the addition of anticoagulant and the PRF is prepared without adding it. The platelet counts in the blood were analyzed and the growth factors were quantitatively measured using ELISA reader. The statistical analysis was performed by using the Chi square test. Results In the quantitative analysis of growth factors LPL showed significant increase of the liberation of growth factors compared to PRP and PRF. Conclusions With the various recent advances in technologies for preparing these platelet concentrates this can be widely used in clinical practice more accurate in the future.R HariprasadT L SuganyaSerin Sarah JohnP Rajesh RajFeby kuriakoseV N AnoopWolters Kluwer Medknow Publicationsarticleelisagrowth factorslyophilized plateletplatelet preparationssurgical additivesPharmacy and materia medicaRS1-441Analytical chemistryQD71-142ENJournal of Pharmacy and Bioallied Sciences, Vol 13, Iss 6, Pp 1696-1699 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	elisa growth factors lyophilized platelet platelet preparations surgical additives Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142
spellingShingle	elisa growth factors lyophilized platelet platelet preparations surgical additives Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142 R Hariprasad T L Suganya Serin Sarah John P Rajesh Raj Feby kuriakose V N Anoop Assessment of growth factors with three different platelet preparations, namely platelet-rich fibrin, platelet-rich plasma, and lyophilized platelet: An In vitro study
description	Assessment of growth factors with three different platelet preparations namely platelet rich fibrin, platelet rich plasma and lyophilized platelet-An invitro study Abstract Enhancing wound healing with patients own blood, particularly the platelet preparations have gained more popularity recently. These platelets excrete large amount of growth factors and cytokines that are associated with the healing process and regeneration. Even though these platelet concentrates are widely used in various forms, the mechanism behind that remains unclear. Therefore, this study aims at investigating the levels of growth factors in three different platelet preparations namely platelet rich plasma (PRP), platelet rich fibrin (PRF) and lyophilized platelets. Materials and Methods Autologous blood for preparing the platelet preparations was obtained from healthy donors aged between 25 to 35 years. The samples were then divided into three experimental groups. The preparation of PRP was done with the addition of anticoagulant and the PRF is prepared without adding it. The platelet counts in the blood were analyzed and the growth factors were quantitatively measured using ELISA reader. The statistical analysis was performed by using the Chi square test. Results In the quantitative analysis of growth factors LPL showed significant increase of the liberation of growth factors compared to PRP and PRF. Conclusions With the various recent advances in technologies for preparing these platelet concentrates this can be widely used in clinical practice more accurate in the future.
format	article
author	R Hariprasad T L Suganya Serin Sarah John P Rajesh Raj Feby kuriakose V N Anoop
author_facet	R Hariprasad T L Suganya Serin Sarah John P Rajesh Raj Feby kuriakose V N Anoop
author_sort	R Hariprasad
title	Assessment of growth factors with three different platelet preparations, namely platelet-rich fibrin, platelet-rich plasma, and lyophilized platelet: An In vitro study
title_short	Assessment of growth factors with three different platelet preparations, namely platelet-rich fibrin, platelet-rich plasma, and lyophilized platelet: An In vitro study
title_full	Assessment of growth factors with three different platelet preparations, namely platelet-rich fibrin, platelet-rich plasma, and lyophilized platelet: An In vitro study
title_fullStr	Assessment of growth factors with three different platelet preparations, namely platelet-rich fibrin, platelet-rich plasma, and lyophilized platelet: An In vitro study
title_full_unstemmed	Assessment of growth factors with three different platelet preparations, namely platelet-rich fibrin, platelet-rich plasma, and lyophilized platelet: An In vitro study
title_sort	assessment of growth factors with three different platelet preparations, namely platelet-rich fibrin, platelet-rich plasma, and lyophilized platelet: an in vitro study
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/42180ab1c18b44d5a08e82c5c0c62b52
work_keys_str_mv	AT rhariprasad assessmentofgrowthfactorswiththreedifferentplateletpreparationsnamelyplateletrichfibrinplateletrichplasmaandlyophilizedplateletaninvitrostudy AT tlsuganya assessmentofgrowthfactorswiththreedifferentplateletpreparationsnamelyplateletrichfibrinplateletrichplasmaandlyophilizedplateletaninvitrostudy AT serinsarahjohn assessmentofgrowthfactorswiththreedifferentplateletpreparationsnamelyplateletrichfibrinplateletrichplasmaandlyophilizedplateletaninvitrostudy AT prajeshraj assessmentofgrowthfactorswiththreedifferentplateletpreparationsnamelyplateletrichfibrinplateletrichplasmaandlyophilizedplateletaninvitrostudy AT febykuriakose assessmentofgrowthfactorswiththreedifferentplateletpreparationsnamelyplateletrichfibrinplateletrichplasmaandlyophilizedplateletaninvitrostudy AT vnanoop assessmentofgrowthfactorswiththreedifferentplateletpreparationsnamelyplateletrichfibrinplateletrichplasmaandlyophilizedplateletaninvitrostudy
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Assessment of growth factors with three different platelet preparations, namely platelet-rich fibrin, platelet-rich plasma, and lyophilized platelet: An In vitro study

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