Biochemical and structural insights into Rab12 interactions with RILP and its family members

Biochemical and structural insights into Rab12 interactions with RILP and its family members

Abstract Alongside its biosynthetic functions, the small GTPase Rab12 negatively regulates mast cell (MC) exocytosis by its interaction with RILP to promote retrograde transport of the MC secretory granules. Given the role of Rab effectors in mediating Rab functions, in this study we used biochemica...

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Autores principales: Jana Omar, Efrat Rosenbaum, Adi Efergan, Bayan Abu Sneineh, Adva Yeheskel, Yuto Maruta, Mitsunori Fukuda, Ronit Sagi-Eisenberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/421863333db34649b334e57221653e1f
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