Biochemical and structural insights into Rab12 interactions with RILP and its family members
Abstract Alongside its biosynthetic functions, the small GTPase Rab12 negatively regulates mast cell (MC) exocytosis by its interaction with RILP to promote retrograde transport of the MC secretory granules. Given the role of Rab effectors in mediating Rab functions, in this study we used biochemica...
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Auteurs principaux: | Jana Omar, Efrat Rosenbaum, Adi Efergan, Bayan Abu Sneineh, Adva Yeheskel, Yuto Maruta, Mitsunori Fukuda, Ronit Sagi-Eisenberg |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/421863333db34649b334e57221653e1f |
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